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TranscriptomicsDysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
The progressive loss of CNS myelin in patients with multiple sclerosis (MS) has been proposed to result from the combined effects of damage to oligodendrocytes and failure of remyelination. A common feature of demyelinated lesions is the presence of oligodendrocyte precursors (OLPs) blocked at a pre...
ORGANISM(S): Mus musculus 
2009-12-10 | E-GEOD-19403 | biostudies-arrayexpress
Genomicsena-DATASET-UCSF-05-11-2013-23:32:06:281-123 - samples
The genetic consequences of cellular transformation by Epstein-Barr-Virus were assessed by comparing whole genome sequences of the original genome (before transformation) and the genome after transformation.
EGAD00001000693 | EGA
Genomicslegitimate academic institutions need to comply with terms of Data Access Agreement to access EGAS00001000323
Data Access Committee EGAC00001000065
EGAC00001000065 | EGA
GenomicsIdentifying genetic consequences of Epstein-Barr Virus transformation by comparing an individual’s genomic DNA with that of its lymphoblastoid cell line.
A detailed analysis of whole genomes can be now achieved with next generation sequencing. Epstein Barr Virus (EBV) transformation is a widely used strategy in clinical research to obtain an unlimited source of a subject’s DNA. Although the mechanism of transformation and immortalization by EBV is re...
EGAS00001000323 | EGA
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