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The replication and life cycle of the influenza virus is governed by an intricate network of intracellular regulatory events during infection, including interactions with an even more complex system of biochemical interactions of the host cell. Computational modeling and systems biology have been su...
The model includes 38 components and 96 biochemical interactions that regulate the differentiation process of major T cell subtypes, i.e., Th1, Th2, Th17 and iTreg cells. Individual components of the model represent lineage-specifying transcription factors (Tbet, GATA3, RORt, and Foxp3), STAT protei...
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