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TranscriptomicsTranscriptional profiling of 5T33MM cells treated in vivo with quisinostat, decitabine or the combination.
Epigenetic modulating agents are under intense investigation for cancer therapy including multiple myeloma. In this study, we investigated the in vivo transcriptional response to epigenetic modulating agents in multiple myeloma using the 5T33MM model with the aim to identify potential clinical rele...
ORGANISM(S): Mus musculus 
2018-02-26 | E-MTAB-3178 | biostudies-arrayexpress
MetabolomicsFour layer multi-omics reveals molecular responses to aneuploidy in Leishmania

Aneuploidy causes system-wide disruptions in the stochiometric balances of transcripts, proteins, and metabolites, often resulting in detrimental effects for the organism. The protozoan parasite Leishmania has an unusually high tolerance for aneuploidy, but the molecular and functional consequenc...

2022-09-19 | MTBLS1612 | MetaboLights
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