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TranscriptomicsGenomic aberrations in distant fields from oral potentially malignant lesions by high resolution DNA flow cytometry and array-CGH
The aim of the study was to address the concept of field cancerization in oral cancer. The presence of genomic aberrations, indicative of chromosomal instability (CIN), in oral distant fields (ODFs) of visually normal and non-dysplastic mucosa at the mirror image from concomitant oral potentially ma...
ORGANISM(S): Homo sapiens 
2011-12-21 | E-GEOD-28906 | biostudies-arrayexpress
TranscriptomicsChromosomal aberrations and aneuploidy in oral potentially malignant lesions: distinctive features for tongue.
The mucosae of the oral cavity are different at the histological level but are all exposed to common genotoxic agents. As a result of this exposure, changes in the mucosal epithelia develop giving rise to Oral Potentially Malignant Lesions (OPMLs), which with time may in turn progress to Oral Squamo...
ORGANISM(S): Homo sapiens 
2011-10-19 | E-GEOD-28868 | biostudies-arrayexpress
TranscriptomicsThe gamma secretase inhibitor LLNle induces apoptosis of human GBM tumor initiating cells
Glioblastomas (GBM) are poorly differentiated astrocytic tumors arising in the Central Nervous System (CNS), which despite aggressive treatments are still characterized by a fatal outcome. Several studies have shown the existence of a subpopulation of cells within glioma tumors displaying cancer ste...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-14581 | biostudies-arrayexpress
TranscriptomicsDemethyl fructiculin A (SCO-1) induces apoptosis by inducing reactive oxygen species in mitochondria
Demethyl fructiculin A is a diterpenoid quinone component of the exudates from Salvia corrugata (SCO-1) leafes. SCO-1 was recently reported to induce anoikis in mammalian cell lines via a molecular mechanism involving the presence of the membrane scavenging receptor CD36. However, experiments perfor...
ORGANISM(S): Homo sapiens 
2010-10-15 | E-GEOD-19846 | biostudies-arrayexpress
TranscriptomicsArabidopsis thaliana wild type mechanical damage (MD) vs herbivore wounding (HW)
Transcriptional profiling of Arabidopsis thaliana wild type (WT) comparing MD (mechanical damage) and HW (herbivore wounding). The differences in the biochemical responses to herbivory seen prompted us to search for less obvious differences between treatments using gene expression profiling. Biologi...
ORGANISM(S): Arabidopsis thaliana 
2012-09-18 | E-GEOD-40923 | biostudies-arrayexpress
TranscriptomicsArabidopsis thaliana wild type mechanical damage (MD) vs Myzus persicae wounding (Myz)
Transcriptional profiling of Arabidopsis thaliana wild type (WT) comparing mechanical damage (MD) and Myzus persicae feeding (Myz). The differences in the biochemical responses to insect feeding seen when compared to the control sample prompted us to search for less obvious differences between the t...
ORGANISM(S): Arabidopsis thaliana 
2012-09-18 | E-GEOD-40924 | biostudies-arrayexpress
TranscriptomicsArabidopsis thaliana wild type control (C) vs Pseudomonas syringae infected (Pseu)
Transcriptional profiling of Arabidopsis thaliana wild type (WT) comparing Mg chloride infiltration (C) and Pseu infection (Pseu). The differences in the biochemical responses to bacterial infection seen when compared to the control sample prompted us to search for less obvious differences between t...
ORGANISM(S): Arabidopsis thaliana 
2012-09-18 | E-GEOD-40922 | biostudies-arrayexpress
ModelsTortolina2015 - Multiple signalling pathway associated with colorectal cancer
No description
2016-02-16 | MODEL1601250000 | BioModels
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