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TranscriptomicsCo-ordinate inhibition of autism candidate genes by topoisomerase inhibitors [Seq]
Topoisomerases are necessary for the expression of neurodevelopmental genes, and are mutated in some patients with autism spectrum disorder (ASD). We have studied the effects of inhibitors of Topoisomerase 1 (Top1) and Topoisomerase 2 (Top2) enzymes on mouse cortical neurons. We find that topoisomer...
ORGANISM(S): Mus musculus 
2013-08-30 | E-GEOD-43526 | biostudies-arrayexpress
GenomicsThe Finland-United States Investigation of NIDDM Genetics (FUSION) Study

The Finland-United States Investigation of NIDDM Genetics (FUSION) study is a long-term effort to identify genetic variants that predispose to type 2 diabetes (T2D) or that impact the variability of T2D-related quantitative traits. The initial effort involved linkage analysis of affected-si...

phs000100.v3.p1 | EGA
TranscriptomicsCo-ordinate inhibition of autism candidate genes by topoisomerase inhibitors
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-08-30 | E-GEOD-43900 | biostudies-arrayexpress
TranscriptomicsCo-ordinate inhibiton of autism candidate genes by topoisomerase inhibitors [array]
Topoisomerases are necessary for the expression of neurodevelopmental genes, and are mutated in some patients with autism spectrum disorder (ASD). We have studied the effects of inhibitors of Topoisomerase 1 (Top1) and Topoisomerase 2 (Top2) enzymes on mouse cortical neurons. We find that topoisomer...
ORGANISM(S): Mus musculus 
2013-08-30 | E-GEOD-43899 | biostudies-arrayexpress
UnknownExpression of naturally ionic liquid-tolerant thermophilic cellulases in Aspergillus niger.
Not available
S-EPMC5744941 | biostudies-literature
UnknownDevelopment of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition.
Not available
S-EPMC11513842 | biostudies-literature
UnknownItaconic acid production is regulated by LaeA in Aspergillus pseudoterreus.
Not available
S-EPMC9440423 | biostudies-literature
UnknownPathology-based staging for HPV-positive squamous carcinoma of the oropharynx.
Not available
S-EPMC5523818 | biostudies-literature
UnknownTOP2B Enzymatic Activity on Promoters and Introns Modulates Multiple Oncogenes in Human Gliomas.
Not available
S-EPMC8818263 | biostudies-literature
TranscriptomicsMAQC
The MicroArray Quality Control (MAQC) project was initiated to address these concerns, as well as other performance and analysis issues. We demonstrate the consistency of results within a platform across test sites as well as the high level of cross-platform concordance in terms of genes identified ...
ORGANISM(S): Homo sapiens 
2006-12-04 | E-TABM-132 | biostudies-arrayexpress
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