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Th2 cells regulate helminth infections, allergic disorders, tumor immunity and pregnancy by secreting various cytokines. It is likely that there are undiscovered Th2-signaling molecules. While steroids are known to be immunoregulators, de novo steroid production from immune cells has not been previo...
ORGANISM(S): Mus musculus 
Bulk RNA sequencing was performed on lung tissue from control and immune cell-specific Cyp11a1 conditional knockout (Cyp11a1fl/fl;Vav1Cre) mice following lipopolysaccharide (LPS)-induced acute lung injury. The experiment was designed to characterise genome-wide transcriptional changes associated wit...
ORGANISM(S): Mus musculus 
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