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TranscriptomicsGene Expression Circulating B Lymphocytes for Smoking Females
B cells were found to be directly associated with the onset and development of many smoking-induced diseases. However, the in vivo molecular response of B cells underlying the female cigarette smoking remains unknown. Using the genome-wide Affymetrix HG-133A GeneChip® microarray, we compared the gen...
ORGANISM(S): Homo sapiens 
2009-12-25 | E-GEOD-18723 | biostudies-arrayexpress
TranscriptomicsMolecular Organization of Drosophila Neuroendocrine Cells by DIMMED: Global Profiling of Pan-Neuronal DIMMED Expression Effects
To amass candidate DIMM targets in addition to Phm (Park et al., 2008a), we used genome-wide microarray profiling by over-expressing DIMM throughout the embryonic nervous system. We compared profiles from experimental (elav>dimm) and control (elav-GAL4) embryos at 22-26 hr and 28-32 hr after egg lay...
ORGANISM(S): Drosophila melanogaster 
2011-09-05 | E-GEOD-31113 | biostudies-arrayexpress
TranscriptomicsGene expression in cutaneous lupus erythematosus
Lesional skin biopsies were taken from patients with active, untreated lupus skin disease (chronic discoid lupus erythematosus, CDLE, n=6; subacute cutaneous lupus erythematosus, SCLE, n=5). Healthy control specimens (HC) were obtained from healthy skin of 5 patients undergoing plastic surgery. In ...
ORGANISM(S): Homo sapiens 
2017-02-24 | E-MTAB-5542 | biostudies-arrayexpress
TranscriptomicsExpression data from Control, Uninfected and BRAF infected cells
Melanocytes within benign human nevi are the paradigm for tumor suppressive senescent cells in a pre-malignant neoplasm. These cells typically contain mutations in either the BRAF or N-RAS oncogene and express markers of senescence, including p16. However, a nevus can contain 10s to 100s of thousand...
ORGANISM(S): Homo sapiens 
2013-08-01 | E-GEOD-46801 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral blood monocytes from acute lymphoblastic leukaemia patients to search for new biomarkers for the monitoring of the minimal residual disease of ALL
The main goal of the research was to find some new biomarkers for the monitoring of the Minimal Residual Disease in Acute Lymphoblastic Leukemia patients. Experiment Overall Design: Lymphocytes from the Periferical Blood Samples of 11 patients with Acute Lymphoblastic Leukemia were purified accordin...
ORGANISM(S): Homo sapiens 
2008-04-05 | E-GEOD-10820 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of soybean cyst nematode-induced syncytia in soybean - time series
Developmental expression profiling of SCN-induced syncytia in soybean (W82) during a compatible interaction.
ORGANISM(S): Glycine max 
2007-06-09 | E-MEXP-876 | biostudies-arrayexpress
TranscriptomicsMitchum Soybean NIL-R vs NIL-S Captured Syncytia
Comparison of syncytia gene expression between soybean near-isogenic lines 7923R (NIL-R) and 7923S (NIL-S) infected with the soybean cyst nematode (PA3).
ORGANISM(S): Glycine max 
2014-10-30 | E-MEXP-3073 | biostudies-arrayexpress
TranscriptomicsExpression data from control and Pbx1-null CMPs and GMPs
The capacity of the hematopoietic system to promptly respond to peripheral demands relies on adequate pools of progenitors able to transiently proliferate and differentiate in a regulated manner. However, little is known about factors that may restrain progenitor maturation to maintain their reserv...
ORGANISM(S): Mus musculus 
2013-03-31 | E-GEOD-30028 | biostudies-arrayexpress
TranscriptomicsReal-time Monitoring of Cisplatin Toxicity on Cancer Cells
Treatment of MCF7 breast cancer cells by cisplatin leads to a very specific metabolic response and an onset of cell death about 10-11 h after beginning of treatment. For more detailed understanding of the molecular processes underlying the specific metabolic response, mRNA was isolated from MCF7 cel...
ORGANISM(S): Homo sapiens 
2011-04-04 | E-GEOD-28274 | biostudies-arrayexpress
TranscriptomicsGene expression changes induced by the pan-PIM inhibitor ETP-39010 in 4 peripheral T cell lymphoma cell lines
Peripheral T cell lymphoma (PTCL) is a very aggressive disease which currently lacks efficient targeted therapy. New therapeutic strategies are needed to improve the very poor outcome of these patients. In these study we hypothesized that PIM kinases could be of therapeutic value in PTCL because we ...
ORGANISM(S): Homo sapiens 
2014-11-14 | E-GEOD-42595 | biostudies-arrayexpress
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