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MetabolomicsAnalysis of sex-specific lipid metabolism of Plasmodium falciparum points to the importance of sphingomyelin for gametocytogenesis
Male and female Plasmodium falciparum gametocytes are the parasite lifecycle stage responsible for transmission of malaria from the human host to the mosquito vector. Not only are gametocytes able to survive in radically different host environments, but they are also precursors for male and female g...
2022-04-05 | MTBLS4137 | MetaboLights
UnknownA preregistered multi-lab replication of Maier et al. (2014, Exp. 4) testing retroactive avoidance.
Not available
S-EPMC7458331 | biostudies-literature
ModelsMaier2022 - Stochastic Dynamics of Type I Interferon Responses
Maier2022 - Stochastic Dynamics of Type I Interferon Responses Our study aims to determine whether and how biochemical noise affects the information transduced in the JAK-STAT signaling pathway and investigate the transition between basal and activated state. To this end, we studied the stochastic ...
2022-10-25 | MODEL2210070001 | BioModels
TranscriptomicsDepletion of Erk1 and Erk2 MAP kinases in primary human keratinocytes
We assessed the effect of RNAi-mediated MAP kinase cascade signaling blockade in primary human keratinocytes. Two sets of siRNA targeting different regions of the Erk1/2 genes were used, enabling identification of off-target siRNA effects. Primary human keratinocytes were electroporated with scra...
ORGANISM(S): Homo sapiens 
2009-05-03 | E-GEOD-15417 | biostudies-arrayexpress
MetabolomicsA general non-self response as part of plant immunity
Plants, like other multicellular lifeforms, are colonized by microorganisms. How plants respond to their microbiota is currently not well understood. We used a phylogenetically diverse set of 39 endogenous bacterial strains from Arabidopsis thaliana leaves to assess host transcriptional and metaboli...
2021-09-13 | MTBLS2522 | MetaboLights
UnknownGrowth of Multilayers of Ionic Liquids on Au(111) Investigated by Atomic Force Microscopy in Ultrahigh Vacuum.
Not available
S-EPMC7676296 | biostudies-literature
TranscriptomicsTranscription profiling by array of M and S molecular forms of Anopheles gambiae at each of three developmental stages
We examined patterns of gene expression in two independent colonies of both M and S molecular forms of Anopheles gambiae at each of three developmental stages of interest: late larvae, sugar-fed virgin females, and gravid females. For each colony, replicates were derived from independent RNA samples...
ORGANISM(S): Anopheles gambiae 
2008-07-10 | E-TABM-344 | biostudies-arrayexpress
UnknownConsidering sex as a biological variable in preclinical research.
Not available
S-EPMC6191005 | biostudies-literature
UnknownComparing the effects of two different strains of mycobacteria, Mycobacterium vaccae NCTC 11659 and M. vaccae ATCC 15483, on stress-resilient behaviors and lipid-immune signaling in rats.
Not available
S-EPMC7749860 | biostudies-literature
TranscriptomicsGene Regulation of Intestinal Porcine Epithelial Cells IPECM-bM-^@M-^QJ2 is Dependent on the Site of Deoxynivalenol Toxicological Action
Here we analysed different mechanisms of apical and basolateral deoxynivalenol (DON) toxicity reflected in the gene expression. We used the jejunum derived, polarized intestinal porcine epithelial cell line IPECM-bM-^@M-^QJ2 as an in vitro cell culture model. Luminal and blood stream DON intoxicatio...
ORGANISM(S): Sus scrofa 
2012-12-31 | E-GEOD-33246 | biostudies-arrayexpress
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