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TranscriptomicsGene expression data from murine heart ventricles E12.5 with and without cardiomyocyte-specific expression of constitutively active IKK2
The transcription factor NF-κB has been associated with a range of pathological conditions of the heart, mainly based on its function as a master regulator of inflammation and pro-survival factor. Here, we addressed the question what effects activation of NF-κB can have during murine heart developme...
ORGANISM(S): Mus musculus 
2015-10-14 | E-MTAB-3971 | biostudies-arrayexpress
ProteomicsGonatopoulos-Pournatzis _eIF4Gmicroexon_P105_Lumos
A This dataset consists of 24 raw MS files, acquired on Orbitrap Fusion Lumos Tribrid mass spectrometer operated in Data Dependent Acquisition mode. B Mouse samples were generated by Thomas Gonatopoulos-Pournatzis. Proteomics sample preparation and mass spectrometric acquisition was performed by Sh...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-12-04 | MSV000084658 | MassIVE
UnknownBeryllium-specific CD4+ T cells induced by chemokine neoantigens perpetuate inflammation.
Not available
S-EPMC8087207 | biostudies-literature
MetabolomicsA general non-self response as part of plant immunity
Plants, like other multicellular lifeforms, are colonized by microorganisms. How plants respond to their microbiota is currently not well understood. We used a phylogenetically diverse set of 39 endogenous bacterial strains from Arabidopsis thaliana leaves to assess host transcriptional and metaboli...
2021-09-13 | MTBLS2522 | MetaboLights
UnknownCytostatic and Cytotoxic Natural Products against Cancer Cell Models.
Not available
S-EPMC6571673 | biostudies-literature
MetabolomicsBioaccumulation of therapeutic drugs by human gut bacteria: secreted metabolite analysis (FIA-MS) (C.saccharolyticum;E.coli;L.plantarum;L.lactis;S.salivarius assays)

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. Interactions at this level have only recently started to being systematically mapped and the main underlying mechanism proposed is chemical transformation of drugs by microbes (biotransformation). Here, we invest...

2021-07-20 | MTBLS1791 | MetaboLights
UnknownWho is at risk of occupational Q fever: new insights from a multi-profession cross-sectional study.
Not available
S-EPMC7045227 | biostudies-literature
TranscriptomicsTranscriptome profiling of the pancreas samples from animals showing autoimmune pancreatitis and chronic pancreatitis
Autoimmune pancreatitis (AIP) is a disease with unclear immunologic triggers. This study shows that the pancreatic stellate cells are involved in the regulation of the immune response and can cause autoimmunity when the NF-κB signalling in these cells is disrupted.
ORGANISM(S): Mus musculus 
2022-03-31 | E-MTAB-7274 | biostudies-arrayexpress
UnknownA 0/1h-algorithm using cardiac myosin-binding protein C for early diagnosis of myocardial infarction.
Not available
S-EPMC9173679 | biostudies-literature
Unknown17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma.
Not available
S-EPMC7811140 | biostudies-literature
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