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ProteomicsA tissue-based draft map of the murine MHC class I immunopeptidome
The array of peptides presented to CD8+ T cells by major histocompatibility complex (MHC) class I molecules is referred to as the MHC class I immunopeptidome. Although the MHC class I immunopeptidome is ubiquitous in mammals and represents a critical component of the adaptive immune system, very lit...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-19 | MSV000084980 | MassIVE
TranscriptomicsMolecular Characterization of In Vivo Adjuvant Activity in Ferrets Vaccinated against Influenza Virus
The 2009 H1N1 influenza pandemic has prompted a significant need for the development of efficient, single-dose, adjuvanted vaccines. Here we investigated the adjuvant potential of CpG oligodeoxynucleotide (ODN) when used with a human seasonal influenza virus vaccine in ferrets. We found that the CpG...
ORGANISM(S): Mustela putorius furo 
2011-02-11 | E-GEOD-27248 | biostudies-arrayexpress
ProteomicsThe effect of interferons on presentation of defective ribosome products as HLA peptides
The class I major histocompatibility complex (MHC) bound peptides, produced from immature proteins that are degraded rapidly are called defective ribosome products (DRiPs). Such DRiPs are possibly involved with early alerting of the immune system about impeding infections, thus bringing about faster...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-25 | MSV000096209 | MassIVE
UnknownProperties and applications of single-chain major histocompatibility complex class I molecules.
Not available
S-EPMC3125553 | biostudies-literature
UnknownMajor histocompatibility complex class I molecules modulate embryonic neuritogenesis and neuronal polarization.
Not available
S-EPMC5776040 | biostudies-literature
UnknownHuman cytomegalovirus-encoded immune modulators partner to downregulate major histocompatibility complex class I molecules.
Not available
S-EPMC2620908 | biostudies-literature
UnknownA common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells.
Not available
S-EPMC2199153 | biostudies-literature
UnknownDirect evidence for conformational dynamics in major histocompatibility complex class I molecules.
Not available
S-EPMC5724011 | biostudies-literature
UnknownPIPLOM: prediction of exogenous peptide loading on major histocompatibility complex class I molecules.
Not available
S-EPMC11904885 | biostudies-literature
UnknownThe mode of action of tapasin on major histocompatibility class I (MHC-I) molecules.
Not available
S-EPMC10040737 | biostudies-literature
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