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TranscriptomicsProfiling expression changes caused by a segmental aneuploid in maize meristem tissues
Segmental aneuploidy refers to the relative excess or deficiency of specific chromosome regions. This condition results in gene dosage imbalance and often causes severe phenotypic alterations in plants and animals. The mechanisms by which gene dosage imbalance effects gene expression and phenotype...
ORGANISM(S): Zea mays 
2010-01-01 | E-GEOD-19212 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of maize segmental aneuploid to study phenotypic and gene expression changes associated with aneuploidy
ABSTRACT: BACKGROUND: While changes in chromosome number that result in aneuploidy are associated with phenotypic consequences such as Down syndrome and cancer, the molecular causes of specific phenotypes and genome-wide expression changes that occur in aneuploids are still being elucidated. RESULTS...
ORGANISM(S): Zea mays 
2008-06-11 | E-GEOD-10243 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of maize zmet2-m1 mutants relative to wild-type
The contribution of epigenetic alterations to natural variation for gene transcription levels remains unclear. In this study, we investigated the functional targets of the maize chromomethylase ZMET2 in multiple inbred lines to determine whether epigenetic changes conditioned by this chromomethylas...
ORGANISM(S): Zea mays 
2008-06-17 | E-GEOD-8188 | biostudies-arrayexpress
TranscriptomicsSpreading of heterochromatin is limited to specific families of maize retrotransposons
Transposable elements have the potential to act as controlling elements to influence the expression of genes. The current paradigm suggests that heterochromatic silencing can spread beyond the borders of the transposable element and influence the chromatin state of neighboring low-copy sequences. ...
ORGANISM(S): Zea mays 
2012-11-26 | E-GEOD-39460 | biostudies-arrayexpress
TranscriptomicsGenomic Distribution of Maize Facultative Heterochromatin Marked by Trimethylation of H3K27
Trimethylation of histone H3 lysine 27 (H3K27me3) plays a critical role in regulating gene expression during plant and animal development. We characterized the genome-wide distribution of H3K27me3 in five developmentally distinct tissues in maize plants of two genetic backgrounds, B73 and Mo17, rep...
ORGANISM(S): Zea mays 
2013-02-20 | E-GEOD-39456 | biostudies-arrayexpress
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