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TranscriptomicsNormal breast tissue of obese women is enriched for macrophage markers and macrophage-associated gene expression
Activation of inflammatory pathways is one plausible mechanism underlying the association between obesity and increased breast cancer risk. However, macrophage infiltration and local biomarkers of inflammation in breast adipose tissue have seldom been studied in association with obesity. Gene expres...
ORGANISM(S): Homo sapiens 
2011-11-08 | E-GEOD-33526 | biostudies-arrayexpress
TranscriptomicsBasal-like Breast Cancer Cells Induce Phenotypic and Genomic Changes in Macrophages
Basal-like breast cancer (BBC) is an aggressive subtype of breast cancer that has no biologically targeted therapy. The interactions of BBCs with stromal cells are important determinants of tumor biology, with inflammatory cells playing well-recognized roles in cancer progression. Despite the fact t...
ORGANISM(S): Homo sapiens 
2013-11-15 | E-GEOD-52292 | biostudies-arrayexpress
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