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TranscriptomicsGene expression profiling after vaccination with the RTS,S candidate malaria vaccine in a controlled human malaria infection study
RTS,S is the sole candidate vaccine shown to provide protection against infection to malaria-naive adults challenged with mosquito-borne homologous falciparum malaria and protection against infection and clinical and severe disease to volunteers in malaria-endemic Africa who were exposed to diverse ...
ORGANISM(S): Homo sapiens 
2017-04-27 | E-MTAB-4629 | biostudies-arrayexpress
ProteomicsComplement System Activation Is a Plasma Biomarker Signature during Malaria in Pregnancy
Malaria in pregnancy (MiP) is a public health problem in malaria-endemic areas, contributing to detrimental outcomes for both mother and fetus. Primigravida and second-time mothers are most affected by severe anaemia complications and babies with low birth weight compared to multi-gravida women. Inf...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD030200 | Pride
Proteomics Complement system Malaria in pregnancy Protein signature 
UnknownEfficacy of two artemisinin-based combinations for the treatment of malaria in pregnancy in India: a randomized controlled trial.
Not available
S-EPMC6030775 | biostudies-literature
ProteomicsComplement System Activation Is a Plasma Biomarker Signature during Malaria in Pregnancy
Malaria in pregnancy (MiP) is a public health problem in malaria-endemic areas, contributing to detrimental outcomes for both mother and fetus. Primigravida and second-time mothers are most affected by severe anaemia complications and babies with low birth weight compared to multi-gravida women. Inf...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD030199 | Pride
Proteomics Complement system Malaria in pregnancy Protein signature 
TranscriptomicsTranscription profiling of human childrens host response to malaria
Subjects are children from Kilifi District Hospital, Kenya, recruited in 2001 malaria season. total RNA extracted from PaxGene tubes, total RNA and Stratagene Universal reference RNA underwent linear amplification (Message Amp, Ambion). Amplified RNA directly labelled Cy5 and Cy3 and hybridised to ...
ORGANISM(S): Homo sapiens 
2005-07-06 | E-SMDB-2669 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse cerebral malaria susceptible and resistant animals
Cerebral malaria (CM) is a leading cause of death in the world. Better understanding of the pathogenesis of this disease is critical for the development of novel therapies. In this work, we investigated temporal gene expression profiles in the brains of CM-susceptible and CM-resistant mice during in...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7814 | biostudies-arrayexpress
UnknownResisting and tolerating P. falciparum in pregnancy under different malaria transmission intensities.
Not available
S-EPMC5513247 | biostudies-literature
TranscriptomicsBulk RNA-seq of the human malaria parasite Plasmodium falciparum 3D7 cultured under different iron conditions
Background: Host iron deficiency is protective against severe malaria as the human malaria parasite Plasmodium falciparum depends on free iron from its host to proliferate. Due to the absence of transferrin, ferritin, ferroportin, and a functional heme oxygenase, the parasite’s essential pathways of...
ORGANISM(S): Plasmodium falciparum 
2024-04-08 | E-MTAB-13411 | biostudies-arrayexpress
MetabolomicsMaHPIC Experiment HuC - Metabolomics of plasma samples from human volunteers infected with Plasmodium vivax
Project Description:
The Malaria Host-Pathogen Interaction Center (MaHPIC) is a transdisciplinary malaria systems biology research program initially supported by an NIH/NIAID contract (HHSN272201200031C, 2012-2017; see http://w...
2018-06-19 | MTBLS665 | MetaboLights
UnknownImpact of Sulfadoxine-Pyrimethamine Resistance on Effectiveness of Intermittent Preventive Therapy for Malaria in Pregnancy at Clearing Infections and Preventing Low Birth Weight.
Not available
S-EPMC4762476 | biostudies-literature
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