the project aim was to evaluate the composition of circulating protein aggregates and compare it between patients affectd with ALS and healthy controls
We have investigated the process of disease-induced functional perturbation and the related transcriptional changes occurring in thoraco-lumbar spinal cord extracted from Sprague-Dawley rats heterozygous for the G93A SOD1 gene mutation (Emerging Model 2148 Het Male, Taconic USA; Wyeth and Amyotrophi...
the aim of the project is to characterise circulating protein aggregates and evaluate their protein composition in order to define new biomarkers of neurodegeneration in blood