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TranscriptomicsHuman adult germline stem cells in question
Conrad et al. Nature 456, 344–349 (2008) have generated human adult germline stem cells (haGSCs) from human testicular tissue, which they claim have similar pluripotent properties to human embryonic stem cells (hESCs). Here we investigate the pluripotency of haGSCs by using global gene-expression ...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-GEOD-17772 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of induced multipotent germline stem cells and other pluripotent stem cells
Spermatogonial stem cells (SSCs) have pluripotent potential. However, frequency of pluripotent cell derivation is low and the mechanism of culture-induced reprogramming remains unknown. Here we report that epigenetic instability of germline stem (GS) cells, cultured SSCs, induces pluripotent cell de...
ORGANISM(S): Mus musculus 
2013-10-21 | E-GEOD-43850 | biostudies-arrayexpress
TranscriptomicsInduction of Pluripotency in Adult Unipotent Germline Stem Cells
Mouse and human stem cells with features similar to those of embryonic stem cells have been derived from testicular cells. Although pluripotent stem cells have been obtained from defined germline stem cells (GSCs) of mouse neonatal testis, only multipotent stem cells have been obtained so far from d...
ORGANISM(S): Mus musculus 
2010-04-09 | E-GEOD-16178 | biostudies-arrayexpress
GenomicsTranscription and Imprinting Dynamics in Developing Postnatal Male Germline Stem Cells
Paternal imprinting initiates in primordial germ cells (PGCs), and is considered largely completed at birth. The resulting postnatal spermatogonial stem cells (SSCs) thenself-renew and proliferate to populate the testicular niche, with sexual maturation enabling productive gametogenesis. mRNA profi...
ORGANISM(S): Mus musculus 
2015-11-09 | E-GEOD-62355 | biostudies-arrayexpress
TranscriptomicsPrepubertal Human Spermatogonia and Mouse Gonocytes Share Conserved Gene Expression of Germline Stem Cell Regulatory
Full title: Prepubertal Human Spermatogonia and Mouse Gonocytes Share Conserved Gene Expression of Germline Stem Cell Regulatory Molecules Oligonucleotide Microarray Analysis Reveals Novel Genes Expressed in Prepubertal Human Spermatogonia and Mouse Gonocytes Four hundred cells were selected for ea...
ORGANISM(S): Homo sapiens 
2009-11-06 | E-GEOD-18914 | biostudies-arrayexpress
TranscriptomicsExpression analysis of laser cut germaria vs laser cut apex of testes
Here we used laser cutting microdissection and RNA amplification to profile the gene expression in wildtype female germaria and male apex of the testes. These tissue contain germline stem cells and early dividing germ cells. Our goal was to identify genes expressed in these cell types. A direct mi...
ORGANISM(S): Drosophila melanogaster 
2012-01-18 | E-GEOD-22686 | biostudies-arrayexpress
TranscriptomicsSilencing of Germline-Expressed Genes by DNA Elimination in Somatic Cells
Chromatin diminution is the programmed elimination of specific DNA sequences during development. It occurs in diverse species, but the function(s) of diminution and the specificity of sequence loss remain largely unknown. Diminution in the nematode Ascaris suum occurs during early embryonic cleavage...
ORGANISM(S): Ascaris suum 
2012-11-13 | E-GEOD-38470 | biostudies-arrayexpress
UnknownIn Vitro Meiosis of Male Germline Stem Cells.
Not available
S-EPMC7664054 | biostudies-literature
UnknownBovine male germline stem-like cells cultured in serum- and feeder-free medium.
Not available
S-EPMC5023554 | biostudies-literature
TranscriptomicsDNMT3L promotes quiescence in postnatal spermatogonial progenitor cells
We analyzed transcriptome profiles of postnatal germ cells and demonstrated that DNMT3L is important for spermatogonial stem/progenitor cell development Examination of wild-type and Dnmt3l knockout smaples in postnatal male germ cells
ORGANISM(S): Mus musculus 
2014-07-03 | E-GEOD-54411 | biostudies-arrayexpress
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