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MetabolomicsFunctional Remodeling of the Gut Microbiome and Metabolome in Primary Idiopathic Male Infertility

Abstract

Background: Primary idiopathic male infertility (PIMI) is a complex condition with unclear biological mechanisms. Increasing evidence indicates that gut microbiome-derived functional and metabolic alterations can influence host physiological processes, yet microbiome-associated fun...

2026-04-07 | MTBLS13886 | MetaboLights
TranscriptomicsExpression data from testes and abdomen in fertile and sterile introgression males
Postmating reproductive isolation is often manifested as hybrid male sterility, for which X-linked genes are over-represented. In contrast, X-linked gene are significantly under-represented among testis-expressing gene.This seeming contradiction may be germane to the X:autosome imbalance hypothesis ...
ORGANISM(S): Drosophila simulans 
2010-05-19 | E-GEOD-21734 | biostudies-arrayexpress
TranscriptomicsComprehensive analysis of genic male sterility-related genes in Brassica rapa using Brassica rapa 300k microarray v2.0
To identify genes associated with genic male sterility (GMS) that could be useful for hybrid breeding in Chinese cabbage (Brassica rapa ssp. pekinensis), floral bud transcriptome analysis was carried out using a B. rapa microarray with 300,000 probes (Br300K). Among 47,548 clones deposited on a Br30...
ORGANISM(S): Brassica rapa subsp. pekinensis 
2013-10-22 | E-GEOD-47665 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of differentially expressed genes from floral buds and flowers of male sterile and fertile lines in watermelon
Male sterility is important mechanism in watermelon for production of hybrid seed. While some fruit development related studies were widely performed in watermelon, there are no reports of profiling gene expression in floral organs of watermelon. RNA-seq analysis was performed in order to identify m...
ORGANISM(S): Citrullus lanatus 
2016-01-04 | E-GEOD-69073 | biostudies-arrayexpress
Proteomicslabel-free analysis of male-sterile line 1355A of cotton
Cotton (Gossypium spp.) is one of the most important economic crops and exhibits yield-improving heterosis in specific hybrid combinations. The genic male-sterility system is the main strategy used for producing heterosis in cotton. To better understand the mechanisms of male sterility in cotton, we...
ORGANISM(S): Gossypium hirsutum 
2019-03-19 | PXD012398 | Pride
Label-free Gossypium Male sterility 
MetabolomicsIntegrated transcriptome and metabolome dynamics with phenotypic traits reveal regulatory basis of male morphotype differentiation in giant freshwater prawn Macrobrachium rosenbergii

This integrated multi-omics resource delineates the molecular and phenotypic trajectories underlying male morphotype differentiation (Blue Claw [BC], Orange Claw [OC], Small Male [SM]) in macrobrachium rosenbergii during determinative developmental stages (100, 110, and 120 days pos...

2025-08-22 | MTBLS12876 | MetaboLights
ProteomicsProteomic Changes of Wheat Male Sterile Anther Induced by Temperature
Wheat, an important human food crop, is very sensitive to temperature changes. Thermosensitive sterile lines (TMS) is a natural material for exploring the effects of anther development and temperature changes on male fertility. In order to study the possible molecular mechanism of regulating protei...
ORGANISM(S): Triticum aestivum (Wheat) 
2022-08-12 | PXD029487 | Pride
Male sterile Wheat Proteome Anther 
TranscriptomicsTranscriptome analysis of male flowers corresponding to anther developmental stages in Cryptomeria japonica
Investigation of gene expression changes among anther development in wild type and male sterile mutant. Male strobili of wild-type were collected at 10 stages with three biological repeats (total 30 samples) and male strobili of mutant were collected at stages 3 to 6 with three biological repeats (t...
ORGANISM(S): Cryptomeria japonica 
2016-03-01 | E-GEOD-64663 | biostudies-arrayexpress
MetabolomicsUntargeted Metabolomics Reveals Serum Metabolic Differences and Key Biomarkers Associated with Growth Traits in Male and Female Macrobrachium rosenbergii of Different Sizes

Macrobrachium rosenbergii is one of the most economically important crustaceans globally, but significant individual growth differences persist even under the same genetic background and rearing conditions, limiting the sustainability of its aquaculture industry. Metabolomics, as a powerful tool ...

2025-11-21 | MTBLS13361 | MetaboLights
TranscriptomicsUncovering small RNA-mediated responses to cold stress in a wheat thermosensitive genic male sterile line by deep sequencing
The male sterility of thermosensitive genic male sterile (TGMS) lines of wheat (Triticum aestivum) is strictly controlled by temperature. The early phase of anther development is especially susceptible to cold stress. MicroRNAs (miRNA) play an important role in plant development and in responses to ...
ORGANISM(S): Triticum aestivum 
2012-03-29 | E-GEOD-36867 | biostudies-arrayexpress
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