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This is an affymetrix array experiment comparing the transcriptome of the Malpighian tubule (or renal tubule) of 7-day adult Oregon R strain Drosophila melanogaster with matched whole fly samples. It is described in:,Wang, J., Kean, L., Yang, J., Allan, A. K., Davies, S. A., Herzyk, P. and Dow, J. A...
ORGANISM(S): Drosophila melanogaster 
modENCODE_submission_5521 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Most terminally differentiated Drosophila tissues are either polyploid or polytene. Unlike normal chromosomes, where th...
ORGANISM(S): Drosophila melanogaster 
Canine heartworm is a widespread and potentially fatal mosquito-borne disease caused by infections with the parasitic nematode, Dirofilaria immitis. We have previously shown that systemic activation of the Toll immune pathway via silencing of the negative regulator Cactus in Aedes aegypti blocks par...
ORGANISM(S): Aedes aegypti 
2024-08-27 | PXD036225 | Pride
Malpighian tubules (MT) gene expression between control and yki3SA gut-tumor-bearing flies.
Ticks (Acari: Ixodida) feed exclusively on blood which lacks essential nutrients such as vitamins and cofactors. These deficiencies are presumably complemented through specific symbiotic microorganisms such as Coxiella – Like Endosymbionts (CLEs) of Rhipicephalus ticks. CLE are localized in speciali...
ORGANISM(S): Coxiella-like endosymbiont of Rhipicephalus sanguineus complex 
2022-02-17 | PXD026817 | Pride
Expression data from Malpighian tubules of wild type and dVHL +/- Drosophila 5-days old female
To investigate the function of Malpighian tubules on host wasting, we established a fly model of tumor-induced wasting by activation of an oncogene Yki in adult intestinal stem cells (ISCs) for 8 days to cause gut-tumor formation and systemic organ wasting and metabolic abnormalities. We then perfor...
ORGANISM(S): Drosophila melanogaster 
2022-05-29 | GSE204866 | GEO
Overexpression of Atg1 using either weaker CGGAL4 or stronger HRGAL4 driver. Both drivers have same expression pattern and are specific for intestine, Malpighian tubules and fat body of the fruit fly Drosophila melanogaster. Weaker Atg1 overexpression results in longer lifespan whereas stronger Atg1...
ORGANISM(S): Drosophila melanogaster 
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