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ProteomicsStructure and organisation of AMPA receptor-TARP complexes in the mammalian cerebellum
AMPA receptors (AMPARs) are multimodal transducers of glutamatergic signals throughout the brain. Their diversity is exemplified in the cerebellum, the brain structure integrating sensorimotor information. At afferent synapses, AMPARs mediate high-frequency excitation, while in Bergmann glia (BG) th...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-02-26 | PXD069620 | Pride
Ampa glutamate receptor Mammalian cerebellum Cry-em 
GenomicsPromoter Decommissioning by the NuRD Chromatin Remodeling Complex Triggers Synaptic Connectivity in the Mammalian Brain
Precise control of gene expression plays fundamental roles in brain development, but the roles of chromatin regulators in neuronal connectivity have remained poorly understood. Here, we find that depletion of the nucleosome remodeling and deacetylation (NuRD) complex in the cerebellar cortex by in v...
ORGANISM(S): Mus musculus 
2014-08-18 | E-GEOD-57758 | biostudies-arrayexpress
UnknownCellular development and evolution of the mammalian cerebellum.
Not available
S-EPMC10808058 | biostudies-literature
TranscriptomicsThe Atoh1 targetome in murine postnatal cerebellum
A relatively small number of proneural transcription factors specify a multitude of neural progenitor populations in the developing mammalian brain. Despite their importance, little is known about their targets, cellular processes they regulate, or what genomic sites they occupy in vivo. We used an ...
ORGANISM(S): Mus musculus 
2011-02-08 | E-GEOD-22111 | biostudies-arrayexpress
GenomicsSelective chemical labeling reveals intragenic enrichment of 5-hydroxymethylcytosine in mouse cerebellum
5-Methylcytosine (5-mC) is an important DNA modification found in eukaryotes that impacts gene regulation and disease pathogenesis. Recently, 5-hydroxymethylcytosine (5-hmC), another form of DNA modification, has been identified in substantial amounts in certain mammalian cell types; however, its ro...
ORGANISM(S): Mus musculus 
2010-12-12 | E-GEOD-25398 | biostudies-arrayexpress
TranscriptomicsExamination of gene expression in cerebellum of mouse strains B6J, B6J-nmf205-/-, B6J-Gcn2-/- and B6J-nmf205-/-;Gcn2-/-.
Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathways we analyzed the brain of B6J-nmf205-/- mice in which neuronal elongation complexes are stalled at...
ORGANISM(S): Mus musculus 
2016-06-15 | E-GEOD-79929 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 6 tissues from Monodelphis domestica to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to gray short-tailed opossum RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcript...
ORGANISM(S): Monodelphis domestica 
2011-10-12 | E-MTAB-3719 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 6 tissues from Homo sapiens to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to human RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcriptome evolution at hig...
ORGANISM(S): Homo sapiens 
2011-10-12 | E-MTAB-3716 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 6 tissues from Macaca mulatta to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to rhesus macaque RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcriptome evoluti...
ORGANISM(S): Macaca mulatta 
2011-10-12 | E-MTAB-3717 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 6 tissues from Mus musculus to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to mouse RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcriptome evolution at hig...
ORGANISM(S): Mus musculus 
2011-10-12 | E-MTAB-3718 | biostudies-arrayexpress
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