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TranscriptomicsTranscription profile of an azole resistant mutant of Mycobacterium truberculosis
We used DNA microarrays to detect differentially expresses genes in a spontaneous mutant of Mycobacterium tuberculosis H37Rv resistant to azoles. We identified three adjacent upregulated genes encoding a transcription regulatory protein and two membrane proteins belonging to the family of RND efflux...
ORGANISM(S): Mycobacterium tuberculosis 
2008-07-31 | E-GEOD-12302 | biostudies-arrayexpress
TranscriptomicsIdentification of the WhiB5 regulon in Mycobacterium tuberculosis H37Rv
We used DNA microarrays to define the M. tuberculosis whiB5 regulon and to study the variation of the global transcription profile in response of its induction. For this purpose we constructed a M. tuberculosis strain in which whiB5 was transcribed from an pristinamycin-inducible promoter and its tr...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2011-08-14 | E-GEOD-30299 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of the Tap efflux pump mutant in Mycobacterium bovis BCG.
We used DNA microarrays to define the physiological roles of the Tap efflux pump in M. bovis BCG during the exponential and the stationary phase of in vitro growth. For this purpose we constructed a M. bovis BCG strain in which the tap gene was inactivated by the insertion of a hygromycin resistance...
ORGANISM(S): Mycobacterium bovis BCG 
2011-12-30 | E-GEOD-32249 | biostudies-arrayexpress
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