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TranscriptomicsGenome Alteration Print (GAP): a tool to visualize and mine complex cancer genomic profiles obtained by SNP-arrays
We describe a method for automatic detection of absolute segmental copy numbers and genotype status in complex cancer genome profiles measured by SNP arrays. The method is based on pattern recognition of segmented and smoothed copy number and allelic imbalance profiles. Overall copy number assignmen...
ORGANISM(S): Homo sapiens 
2009-10-29 | E-GEOD-18799 | biostudies-arrayexpress
TranscriptomicsBeta-catenin status in pediatric medulloblastomas
Medulloblastoma is the most frequent malignant pediatric brain tumor. Considerable efforts are dedicated to identify markers that help to refine treatment strategies. The activation of the Wnt/beta-catenin pathway occurs in 10-15% of medulloblastomas and has been recently described as a marker for f...
ORGANISM(S): Homo sapiens 
2009-02-02 | E-GEOD-12992 | biostudies-arrayexpress
TranscriptomicsGenetic heterogeneity versus molecular analysis of prion susceptibility in neuroblasma N2a sublines
The neuroblastoma-derived cell line N2a is permissive to certain prion strains but resistant sublines unable to accumulate the pathological proteinase-K resistant form of the prion protein can be isolated. We compared for gene expression and phenotypes different N2a sublines that were susceptible or...
ORGANISM(S): Mus musculus 
2010-06-19 | E-GEOD-5374 | biostudies-arrayexpress
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