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Heterochromatin is a key feature of eukaryotic genomes that serves important regulatory and structural roles in regions such as centromeres. In fission yeast, maintenance of existing heterochromatic domains relies on positive feedback loops involving histone methylation and non-coding RNAs. However,...
ORGANISM(S): Schizosaccharomyces pombe 927 
2025-02-14 | PXD050937 | Pride
Comparison of DNA methylation levels of chromosome 18 between placentas and blood cells of pregnant women Extracted DNA from 5 cases of placental tissues and 5 cases of maternal blood cell was subjected to MeDIP (methylated DNA immunoprecipitation) and hybridized to Affymetrix GeneChip® Human Tiling...
ORGANISM(S): Homo sapiens 
The aim of this experiment was to identify specific subsets of monocytes, dendritic cells, macrophages and structural cells including epithelial cells, endothelial cells and stromal cells in the murine uterus, across all reproductive cycle stages via single cell RNA sequencing. Samples were FACS-enr...
ORGANISM(S): Mus musculus 
The JAK/STAT pathway is an essential signalling cascade required for multiple processes during both development and for adult homeostasis. A key question in understanding this pathway is how it is regulated in different cell contexts. Here we have examined how endocytic processing contributes to sig...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-09-29 | PXD020719 | Pride
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