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UnknownA hormonal cue promotes timely follicle cell migration by modulating transcription profiles.
Not available
S-EPMC5758037 | biostudies-literature
TranscriptomicsAMPK and calcineurin induced longevity is mediated by CRTC-1 and CREB
AMPK (AAK-2) and calcineurin (TAX-6) mediate longevity exclusively through post-translational modification of CRTC-1, the sole C. elegans CRTC (CREB regulated transcriptional coactivator). We performed microarrays to examine the transcriptional responses elicited by the pro-longevity: activation of ...
ORGANISM(S): Caenorhabditis elegans 
2010-11-20 | E-GEOD-25513 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma (PDAC)
Determine methylation pattern in PDAC a genome-wide analysis was performed in a cohort of 167 PDAC and 29 adjacent pancreatic tissues samples using the Infinium 450k methylation arrays (Illumina). 167 pancreatic tumors (PDAC) x 29 adjacent -non tumor samples.
ORGANISM(S): Homo sapiens 
2014-07-08 | E-GEOD-49149 | biostudies-arrayexpress
TranscriptomicsRoute specific dermal responses to vaccinia virus infection
Transcriptional profiles of rabbit skin infected via the intradermal or scarification route of infeciton assessing the early time post infection. Transcriptional profiles were assessed at 4hrs, 24hrs, and 48hrs post infection for each route of infection. Transcript variation is as compared to normal...
ORGANISM(S): Oryctolagus cuniculus 
2014-05-13 | E-GEOD-57564 | biostudies-arrayexpress
UnknownAdar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling.
Not available
S-EPMC10110501 | biostudies-literature
GenomicsGoT2D: Genetics of Type 2 Diabetes, a study of the the genetic architecture of type 2 diabetes using low pass whole genome sequencing and high density SNP genotyping in 2,657 individuals.
The Genetics of Type 2 Diabetes Consortium (GoT2D) is a collaboration between the University of Michigan, the Broad Institute and the Wellcome Trust Centre for Human Genetics. The overall aim is to extend upon recent efforts, such as genome-wide association studies (GWAS) and large scale meta-analys...
EGAS00001001459 | EGA
UnknownSafety and pharmacokinetics of VRC07-523LS administered via different routes and doses (HVTN 127/HPTN 087): A Phase I randomized clinical trial.
Not available
S-EPMC11251612 | biostudies-literature
UnknownPharmacokinetic interaction assessment of an HIV broadly neutralizing monoclonal antibody VRC07-523LS: a cross-protocol analysis of three phase 1 trials in people without HIV.
Not available
S-EPMC11837431 | biostudies-literature
GenomicsGenomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis.
Oesophageal adenocarcinoma (EAC) incidence is rapidly increasing in Western countries. A better understanding of EAC underpins efforts to improve early detection and treatment outcomes. While large EAC exome sequencing efforts to date have found recurrent loss-of-function mutations, oncogenic drivin...
EGAS00001000750 | EGA
UnknownKey Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction.
Not available
S-EPMC7652061 | biostudies-literature
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