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TranscriptomicsTranscription profiling of acute telomere dysfunction in the mouse liver using adenoviral mediated, transient expression of a dominant negative version of TRF
Telomere dysfunction induces two types of cellular responses: cellular senescence and apoptosis. Here we analyzed the influence of the cellular level of telomere dysfunction and the role of p53 on induction of apoptosis and senescence in mouse liver using the experimental system of adenoviral mediat...
ORGANISM(S): Mus musculus 
2006-11-21 | E-MEXP-141 | biostudies-arrayexpress
TranscriptomicsDirect reprogramming of hepatic myofibroblasts into hepatocytes in vivo attenuates liver fibrosis
Direct induction of induced hepatocytes (iHeps) from fibroblasts holds potential as a strategy for regenerative medicine, but until now has only been shown in culture settings. Here, we describe in vivo iHep formation using transcription factor induction and genetic fate tracing in mouse models of c...
ORGANISM(S): Mus musculus 
2016-02-22 | E-GEOD-76843 | biostudies-arrayexpress
UnknownCultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018.
Not available
S-EPMC6933546 | biostudies-literature
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