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UnknownAmylin and leptin activate overlapping signalling pathways in an additive manner in mouse GT1-7 hypothalamic, C₂C₁₂ muscle and AML12 liver cell lines.
Not available
S-EPMC3780406 | biostudies-literature
TranscriptomicsTranscription profiling of mouse C2C12 myotubes treated overnight with 500 uM palmitate or 1% bovine serum albumin control to identify mediators of obesity-linked reductions in PGC-1
To identify mediators of obesity-linked reductions in PGC-1, we tested the effects of cellular nutrients in C2C12 myotubes. While overnight exposure to high insulin, glucose, glucosamine, or amino acids had no effect, saturated fatty acids (FA) potently reduced PGC-1a and b mRNA expression. Exper...
ORGANISM(S): Mus musculus 
2007-11-15 | E-GEOD-6766 | biostudies-arrayexpress
UnknownCirculating total and H-specific GDF15 levels are elevated in subjects with MASLD but not in hyperlipidemic but otherwise metabolically healthy subjects with obesity.
Not available
S-EPMC11102634 | biostudies-literature
UnknownA prospective study of maternal prenatal weight and offspring cardiometabolic health in midchildhood.
Not available
S-EPMC4254266 | biostudies-literature
UnknownSelective capacity of metreleptin administration to reconstitute CD4+ T-cell number in females with acquired hypoleptinemia.
Not available
S-EPMC3587204 | biostudies-literature
TranscriptomicsGene expression profile of PBMCs in response to metreleptin treatment at different time points.
we evaluated the modulation of gene expression profile in PBMCs from patients with hypotalamic amenorrhea. We have employed whole genome microarray expression profiling as a discovery platform to identify genes differentially expressed upon metreleptin treatment at different time points, week 12, 24...
ORGANISM(S): Homo sapiens 
2013-03-04 | E-GEOD-36990 | biostudies-arrayexpress
UnknownPatient-specific deep offline artificial pancreas for blood glucose regulation in type 1 diabetes
Not available
S-EPMC12945307 | biostudies-literature
UnknownThe Effect of the Mediterranean Diet on Metabolic Health: A Systematic Review and Meta-Analysis of Controlled Trials in Adults.
Not available
S-EPMC7692768 | biostudies-literature
UnknownEfficacy of metreleptin in obese patients with type 2 diabetes: cellular and molecular pathways underlying leptin tolerance.
Not available
S-EPMC3114380 | biostudies-literature
UnknownRegulation of mouse hepatic genes in response to diet induced obesity, insulin resistance and fasting induced weight reduction.
Not available
S-EPMC1201568 | biostudies-literature
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