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ProteomicsHepG2 HLA-I immunopeptidome by immunoprecipitation
This study utilized mass spectrometry-based proteogenomic profiling to identify the HLA-I immunopeptidome enriched from HepG2 cell. HepG2 WES-based and the COSMIC-based mutation database were generated and utilized to identify HepG2-specific mutant immunopeptides
ORGANISM(S): Homo Sapiens 
PXD045203 |
ProteomicsMitochondrial Proteomics Uncovers Myeloid S100A9 Deficiency Promotes Liver Injury and Fibrosis Regression via Mitochondrial Metabolic Reprogramming of Macrophages
Macrophage-mediated inflammation has been implicated in the pathogenesis of liver fibrosis. Metabolic reprogramming involves in the transition of macrophages from a pro-inflammatory M1-phenotype toward an anti-inflammatory M2-phenotype. S100A9 is highly expressed in activated macrophages and promote...
ORGANISM(S): Mus Musculus 
2025-11-03 | PXD070260 |
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