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ProteomicsGlobal proteomic and phosphoproteomic analysis of WT HEC-50B and MAPK14-/- HEC-50B cells cultured as 2D monolayers and 3D spheroids.
The molecular underpinnings of High Grade Endometrial Carcinoma (HGEC) metastatic growth and survival are poorly understood. Here we show that ascites-derived and primary tumor HGEC cell lines in 3D spheroid culture faithfully recapitulate key features of malignant peritoneal effusion and exhibit fu...
ORGANISM(S): Homo sapiens (Human) 
2025-10-07 | PXD053011 | Pride
Endometrial cancer P38a Mapk14 3d spheroids 
TranscriptomicsRNA-Seq analysis of Mapk14 knockout and myogenic differentiation in C2C12 cells
This study investigates the role of p38/Mapk14 in myogenic differentiation using C2C12 mouse myoblast cells. Wild-type and Mapk14 knockout cells in the logarithmic growth phase were cultured in growth medium (GM) or differentiation medium (DM) for 5 days. RNA was extracted for sequencing to examine ...
ORGANISM(S): Mus musculus 
2026-01-07 | GSE315765 | GEO
Genomics
Single-cell transcriptomic analysis of MAPK14 +/+ HEC-50B cells and MAPK14 -/- HEC50B cells cultured as 3D spheroids
PRJNA1191544 | ENA
GenomicsMAPK14 Governs Mammalian Müller glia Fate Determination between Gliosis and Reprogramming
MAPK14 Governs Mammalian Müller glia Fate Determination between Gliosis and Reprogramming
PRJNA1402154 | ENA
UnknownIn silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor.
Not available
S-EPMC7718943 | biostudies-literature
UnknownMAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy.
Not available
S-EPMC3429546 | biostudies-literature
GenomicsMAPK14 Governs Mammalian Müller glia Fate Determination between Gliosis and Reprogramming [scRNA-Seq]
MAPK14 Governs Mammalian Müller glia Fate Determination between Gliosis and Reprogramming [scRNA-Seq]
PRJNA1402153 | ENA
UnknownTargeting neuronal MAPK14/p38α activity to modulate autophagy in the Alzheimer disease brain.
Not available
S-EPMC5173254 | biostudies-literature
GenomicsThe MAPK14/MAPK7/BCL6B pathway creates a positive feedback loop to drive spermatogonial stem cell (SSC) self-renewal via ROS amplification.
The MAPK14/MAPK7/BCL6B pathway creates a positive feedback loop to drive spermatogonial stem cell (SSC) self-renewal via ROS amplification.
PRJNA484802 | ENA
UnknownGSNOR negatively regulates the NLRP3 inflammasome via S-nitrosation of MAPK14.
Not available
S-EPMC11143353 | biostudies-literature
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