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TranscriptomicsInteraction between endothelium and chronic lymphocytic leukemia B-cells rescues from apoptosis and modulates gene expression profile of leukemic cells
Chronic lymphocytic leukemic B cells (CLL) reside in close contact with activated endothelial cells (EC) in infiltrated tissues. Here, we investigated the interactions between EC and CLL cells, highlighting molecular networks involved in this cellular crosstalk. We co-cultured purified CLL cells on ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-28787 | biostudies-arrayexpress
UnknownEndothelin-1 promotes survival and chemoresistance in chronic lymphocytic leukemia B cells through ETA receptor.
Not available
S-EPMC4046988 | biostudies-literature
TranscriptomicsTranscription profiling of human untreated B-cell chronic lymphocytic leukemia
B-cell chronic lymphocytic leukemia (B-CLL) shows an incredibly high heterogeneity in the clinical course, spanning from rapidly aggressive to completely indolent behaviour. In order to identify the correspondent gene expression variability, we investigated 29 cases of untreated B-CLL using microarr...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-4207 | biostudies-arrayexpress
UnknownTargeting neoplastic B cells and harnessing microenvironment: the "double face" of ibrutinib and idelalisib.
Not available
S-EPMC4459446 | biostudies-literature
UnknownANGPT2 promoter methylation is strongly associated with gene expression and prognosis in chronic lymphocytic leukemia.
Not available
S-EPMC3781191 | biostudies-literature
UnknownDried Urine Microsampling Coupled to Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) for the Analysis of Unconjugated Anabolic Androgenic Steroids.
Not available
S-EPMC7397045 | biostudies-literature
UnknownIdelalisib impairs T-cell-mediated immunity in chronic lymphocytic leukemia.
Not available
S-EPMC6269319 | biostudies-literature
UnknownDried Volumetric Microsampling Approaches for the Therapeutic Drug Monitoring of Psychiatric Patients Undergoing Clozapine Treatment.
Not available
S-EPMC9198272 | biostudies-literature
UnknownImmunoglobulin gene mutations and frequent use of VH1-69 and VH4-34 segments in hepatitis C virus-positive and hepatitis C virus-negative nodal marginal zone B-cell lymphoma.
Not available
S-EPMC1850410 | biostudies-literature
UnknownBTK Inhibition Impairs the Innate Response Against Fungal Infection in Patients With Chronic Lymphocytic Leukemia.
Not available
S-EPMC7485008 | biostudies-literature
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