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Background: MicroRNAs (miRNAs) are small, non-coding, RNA molecules which regulate numerous cellular processes. Specific miRNA may be abnormally down-regulated or up-regulated in colorectal cancer and have been found associated with prognosis or response to treatments. However, no study has ever ad...
ORGANISM(S): Homo sapiens 
This investigation aims at identifying differentially expressed miRNA between two cell lines, MLS 402-91 (sensitive to trabectidin) and MLS 402-91/ET (resistant to trabectidin).
ORGANISM(S): Homo sapiens 
Gene expression profiles of 402-91 FUS-CHOP type I cells have been compared to 402-91/ET cells made resistant to Trabectedin Experiments were performed on purified RNA from independent batches of 402-91 and 402-91/ET cells without drug treatment.
ORGANISM(S): Homo sapiens 
Various studies have shown that aerobic exercise can prevent or alleviate cancer-induced muscle wasting. To reproduce at least partially in vitro some molecular differences of aerobic muscle exercise that are independent from systemic inflammation or the hormonal milieu, we infected fully different...
ORGANISM(S): Mus musculus 
The purpose of experiments consisted in studying the mode of action of Trabectedin in Desmoplastic Small Round Cell Tumor (DSRCT). In order to investigate the effects of Trabectedin in the expression of EWS-WT1 target genes in relation to the drug growth inhibitory effect, the JN-DSCRT-1 cell line w...
ORGANISM(S): Homo sapiens 
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