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TranscriptomicsAlteration in global transcriptome after Notch inhibition with gamma-secretase inhibitor MRK003 in Glioblastoma Cells
We used DNA microarrays to compare RNA transcript expression from various glioma neurospheres after treatment with gamma-secretase inhibitor MRK003. Four glioma cell lines grown as neurospheres (GBM1, GBM2, GBM10 and GBM14) were treated two concentrations of with gamma-secretase inhibitor MRK003 (Hi...
ORGANISM(S): Homo sapiens 
2015-08-07 | E-GEOD-71769 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human xenograft laboratory models and primary tumors of small cell lung cancer
Gene expression was measured on the Affymetrix platform in primary xenografts, xenograft-derived cell lines, secondary xenografts, normal lung, and primary tumors obtained from chemotherapy naive Small Cell Lung Cancer (SCLC). The SCLC primary xenografts were serially propagated in vivo in immunodef...
ORGANISM(S): Homo sapiens 
2009-06-05 | E-GEOD-15240 | biostudies-arrayexpress
TranscriptomicsGene expression in a Highly Tumorigenic Cells (HTC) purified from Urothelial Cancer
We used DNA microarrays to compare RNA transcript expression from distinct cell populations sorted by FACS with an antibody against the 67Kd laminin receptor (67LR), and showing distinct tumorigenicity in vivo. Sorted cells were derived by digesting xenografted sw 780 tumors into single cell suspens...
ORGANISM(S): Homo sapiens 
2009-05-28 | E-GEOD-16255 | biostudies-arrayexpress
TranscriptomicsAndrogen dependent gene expression profiling of the urogenital sinus
Cancer cells differentiate along specific lineages that largely determine their clinical and biologic behavior. Distinct cancer phenotypes from different cells and organs likely result from unique gene expression repertoires established during lineage commitment in the embryo and maintained after ma...
ORGANISM(S): Mus musculus 
2008-12-03 | E-GEOD-12077 | biostudies-arrayexpress
UnknownERK phosphorylation is predictive of resistance to IGF-1R inhibition in small cell lung cancer.
Not available
S-EPMC3681842 | biostudies-literature
UnknownBlockage of interleukin-1β with canakinumab in patients with Covid-19.
Not available
S-EPMC7733468 | biostudies-literature
MetabolomicsNMR-based metabolomics identifies patients at high risk of death within two years after acute myocardial infarction in the AMI-Florence II cohort
Risk stratification and management of acute myocardial infarction patients continue to be challenging despite considerable efforts made in the last decades by many clinicians and researchers. The aim of this study was to investigate the metabolomic fingerprint of acute myocardial infarction using nu...
2018-10-02 | MTBLS395 | MetaboLights
UnknownMultiNEP: a multi-omics network enhancement framework for prioritizing disease genes and metabolites simultaneously.
Not available
S-EPMC10250081 | biostudies-literature
UnknownIsolation of microarray-quality RNA from primary human cells after intracellular immunostaining and fluorescence-activated cell sorting.
Not available
S-EPMC3627819 | biostudies-literature
UnknownAn R package for divergence analysis of omics data.
Not available
S-EPMC8021195 | biostudies-literature
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