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TranscriptomicsGene expression in a Highly Tumorigenic Cells (HTC) purified from Urothelial Cancer
We used DNA microarrays to compare RNA transcript expression from distinct cell populations sorted by FACS with an antibody against the 67Kd laminin receptor (67LR), and showing distinct tumorigenicity in vivo. Sorted cells were derived by digesting xenografted sw 780 tumors into single cell suspens...
ORGANISM(S): Homo sapiens 
2009-05-28 | E-GEOD-16255 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human xenograft laboratory models and primary tumors of small cell lung cancer
Gene expression was measured on the Affymetrix platform in primary xenografts, xenograft-derived cell lines, secondary xenografts, normal lung, and primary tumors obtained from chemotherapy naive Small Cell Lung Cancer (SCLC). The SCLC primary xenografts were serially propagated in vivo in immunodef...
ORGANISM(S): Homo sapiens 
2009-06-05 | E-GEOD-15240 | biostudies-arrayexpress
TranscriptomicsAlteration in global transcriptome after Notch inhibition with gamma-secretase inhibitor MRK003 in Glioblastoma Cells
We used DNA microarrays to compare RNA transcript expression from various glioma neurospheres after treatment with gamma-secretase inhibitor MRK003. Four glioma cell lines grown as neurospheres (GBM1, GBM2, GBM10 and GBM14) were treated two concentrations of with gamma-secretase inhibitor MRK003 (Hi...
ORGANISM(S): Homo sapiens 
2015-08-07 | E-GEOD-71769 | biostudies-arrayexpress
TranscriptomicsAndrogen dependent gene expression profiling of the urogenital sinus
Cancer cells differentiate along specific lineages that largely determine their clinical and biologic behavior. Distinct cancer phenotypes from different cells and organs likely result from unique gene expression repertoires established during lineage commitment in the embryo and maintained after ma...
ORGANISM(S): Mus musculus 
2008-12-03 | E-GEOD-12077 | biostudies-arrayexpress
MetabolomicsNMR-based metabolomics identifies patients at high risk of death within two years after acute myocardial infarction in the AMI-Florence II cohort
Risk stratification and management of acute myocardial infarction patients continue to be challenging despite considerable efforts made in the last decades by many clinicians and researchers. The aim of this study was to investigate the metabolomic fingerprint of acute myocardial infarction using nu...
2018-10-02 | MTBLS395 | MetaboLights
Genomics
Tumor-infiltrating lymphocytes RNASeq
PRJNA1120915 | ENA
TranscriptomicsGene expression profiling of HIV-1 latently infected memory CD4+ T cells
Suppressive HAART does not eradicate HIV-1 and viral DNA persists as a stably integrated form in the absence of viral particle production. As a consequence, latent reservoirs are refractory to antiretroviral drugs and invisible to immune surveillance. The largest latent reservoir consists of resting...
ORGANISM(S): Homo sapiens 
2013-03-15 | E-GEOD-40550 | biostudies-arrayexpress
UnknownRanolazine in patients with chronic coronary syndromes: real-world data provide new evidence on the antiarrhythmic properties of the drug.
Not available
S-EPMC12705168 | biostudies-literature
TranscriptomicsSox9 mediated differential gene expression was assessed in prostaspheres derived from urogenital sinus epithelial cells
Prostate cancer is one of the most common malignancies and the second leading cause of death from cancer in men. The molecular mechanisms driving prostate carcinogenesis are complex; with several lines of evidence suggesting that the re-expression of conserved developmental programs play a key role....
ORGANISM(S): Mus musculus 
2013-01-01 | E-GEOD-35419 | biostudies-arrayexpress
UnknownClinical Phenotype and Prognostic Significance of Frailty in Transthyretin Cardiac Amyloidosis.
Not available
S-EPMC12046810 | biostudies-literature
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