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MARCKS and lnc-MARCKS act as inflammation regulators
The goals of this study are to reveal the target transcriptome of MARCKS and lnc-MARCKS in TLR2 signaling pathway. We knocked down MARCKS, or over-expressed lnc-MARCKS in THP1-derived macrophages stimulated with Pam3CSK4 for 8 hours. And compared the transcriptomes of the editing cells with control ...
ORGANISM(S): Homo sapiens 
2019-01-09 | GSE108680 | GEO
WT immortorized mouse macrophages and CISPR CAS 9 mediated Myristoylated, Alanine-rich C-kinase Substrate knockout ΔMARCKS were treated with LPS for 1h, 6h, 24h. No treatment both WT and ΔMARCKS were use as a control experiment. The label free quantification were prefromed using
ORGANISM(S): Mus musculus (Mouse) 
2023-11-20 | PXD042097 | Pride
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