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TranscriptomicsTranscription profiling of reference RNA samples using automated cDNA sysnthesis and labeling to investigate effect on reproducibility
Not available
ORGANISM(S): Homo sapiens 
2009-08-17 | E-TABM-749 | biostudies-arrayexpress
TranscriptomicsA novel copper-responsive regulon in Mycobacterium tuberculosis.
In this study, we report the identification of a five-locus copper-inducible regulon in Mycobacterium tuberculosis. The identification of a copper responsive regulon unique to pathogenic Mycobacteria suggests copper homeostasis must be maintained during an infection. WT and mutant Mtb cells were gro...
ORGANISM(S): Mycobacterium tuberculosis 
2010-10-27 | E-GEOD-23498 | biostudies-arrayexpress
TranscriptomicsA Novel Copper Responsive Regulon in Mycobacterium tuberculosis strains mpA and pafA
In this study, we report the identification of a five-locus copper-inducible regulon in Mycobacterium tuberculosis. The identification of a copper responsive regulon unique to pathogenic Mycobacteria suggests copper homeostasis must be maintained during an infection. WT and mutant Mtb cells were gro...
ORGANISM(S): Mycobacterium tuberculosis 
2011-11-01 | E-GEOD-24968 | biostudies-arrayexpress
TranscriptomicsGene expression of resting memory, resting naive and in vitro activated memory CD8+CD127+ T cells from spleen and bone marrow (BM)
To understand differences between resting and activated memory CD8+ T cells, we compared the global gene expression of ex vivo isolated naive and spleen and BM memory cells to in vitro activated spleen and BM memory cells. Single cell suspension from the spleen and bones of aged C57BL/6 mice were pr...
ORGANISM(S): Mus musculus 
2015-02-05 | E-GEOD-62691 | biostudies-arrayexpress
GenomicsEpo-Induced Erythroid Maturation Is Dependent on Plcγ1 Signaling
Erythropoiesis is a tightly regulated process. Development of red blood cells occurs through differentiation of hematopoietic stem cells into more committed progenitors and finally into erythrocytes. Binding of erythropoietin to its receptor (EpoR) is strictly required for erythropoiesis as it promo...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-60087 | biostudies-arrayexpress
ProteomicsLongitudinal Analysis of the Lung Proteome Reveals Persistent Repair Months after Mild to Moderate COVID-19
In order to assess the restoration of homeostasis in the lung proteome after COVID-19 infection, we performed bronchoalveolar lavage on 45 patients with mild to moderate disease at three phases (acute, recovery, convalescence) over a year. Changes in proteins were assessed using a multimodal approac...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-05-30 | MSV000094898 | MassIVE
UnknownThe National Lung Screening Trial: overview and study design.
Not available
S-EPMC3009383 | biostudies-literature
GenomicsIntegrative genomic and transcriptomic analysis of adult leiomyosarcoma (HIPO-028, HIPO-018, HIPO-021)
Leiomyosarcoma (LMS) is an aggressive mesenchmyal malignancy with few therapeutic options. The mechanisms underlying LMS development, including clinically actionable genetic vulnerabilities, are largely unknown. We performed genomic and transcriptomic profiling of a large cohort of LMS tumors and id...
EGAS00001002437 | EGA
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
UnknownReduced lung-cancer mortality with low-dose computed tomographic screening.
Not available
S-EPMC4356534 | biostudies-literature
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