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TranscriptomicsBiological Impact Of Environmental Toxicants In Vitro
Exposure to cigarette smoke is a leading cause of lung diseases including chronic obstructive pulmonary disease and cancer. Cigarette smoke is a complex aerosol containing over 6000 chemicals, and thus it is difficult to determine individual contributions to overall toxicity, and the molecular mecha...
ORGANISM(S): Homo sapiens 
2014-05-09 | E-MTAB-2080 | biostudies-arrayexpress
TranscriptomicsIN VITRO SYSTEMS TOXICOLOGY ASSESSMENT OF A PROTOTYPIC MODIFIED RISK TOBACCO PRODUCT SHOWS REDUCED TOXICITY COMPARED TO A CONVENTIONAL CIGARETTE
The toxicity and potential associated molecular mechanism of a reference cigarette, 3R4F and THS2.2 a candidate modified risk tobacco products ((p)MRTP) were investigated with human bronchial epithelial cells using high-throughput screening and whole transcriptomics analysis.
ORGANISM(S): Homo sapiens 
2016-01-05 | E-MTAB-3738 | biostudies-arrayexpress
TranscriptomicsComparison of the Biological Effects of Long-Term Treatment of Human Bronchial Epithelial Cells with 3R4F Cigarette Smoke or THS2.2 Aerosol Total Particulate Matter (mRNA data)
Cigarette smoking is the leading cause of lung cancer worldwide. Carcinogens in smoke produced during the combustion of cigarette tobacco are responsible for airway epithelial changes underlying lung carcinogenesis. Reduction of harmful constituents by heating rather than combusting tobacco would be...
ORGANISM(S): Homo sapiens 
2018-03-08 | E-MTAB-5697 | biostudies-arrayexpress
TranscriptomicsComparison of the Biological Effects of Long-Term Treatment of Human Bronchial Epithelial Cells with 3R4F Cigarette Smoke or THS2.2 Aerosol Total Particulate Matter (microRNA data)
Cigarette smoking is the leading cause of lung cancer worldwide. Carcinogens in smoke produced during the combustion of cigarette tobacco are responsible for airway epithelial changes underlying lung carcinogenesis. Reduction of harmful constituents by heating rather than combusting tobacco would be...
ORGANISM(S): Homo sapiens 
2018-03-08 | E-MTAB-6119 | biostudies-arrayexpress
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