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MetabolomicsRNA virus-induced metabolic reprogramming in a bloom-forming, marine diatom
• Diatoms are a widespread group of phytoplankton that disproportionately influence the global carbon cycle through substantial contributions to primary production and carbon export in the ocean. Marine viruses are major drivers of host metabolic reprogramming and mortality and it is increasingly cl...
2026-10-09 | MTBLS15467 | MetaboLights
MetabolomicsMicroRNA-mediated regulation of lipid metabolism in virus-infected Emiliania huxleyi.
The interactions between Emiliania huxleyi and E. huxleyi virus (EhV) regulate marine carbon and sulfur biogeochemical cycles and play a prominent role in global climate change. As a large DNA virus, EhV has developed a novel 'virocell metabolism' model to meet its high metabolic needs. Although it ...
2024-01-16 | MTBLS5178 | MetaboLights
MetabolomicsCell-to-cell heterogeneity drives host-virus coexistence in a bloom-forming alga

Algal blooms drive global biogeochemical cycles of key nutrients in the oceans and serve as hotspots for biological interactions. The massive spring blooms of the cosmopolitan coccolithophore Emiliania huxleyi (E. huxleyi) are often infected by the lytic Emiliania huxleyi

2024-01-04 | MTBLS1956 | MetaboLights
MetabolomicsGrowth Substrate and Prophage Induction Collectively Influence Metabolite and Lipid Profiles in a Marine Bacterium

Bacterial growth substrates influence a variety of biological functions, including the biosynthesis and regulation of lipid intermediates. The extent of this rewiring is not well understood nor has it been considered in the context of virally-infected cells. Here, we use a one-host-two-temperate ...

2022-08-04 | MTBLS5345 | MetaboLights
MetabolomicsIntracellular metabolites from an experimental manipulation of marine microorganisms
The marine environment holds one of the largest pools of reduced organic carbon on Earth. Within this organic carbon are metabolites produced as a result of microbial activity. This project considers the effects of predation and viral lysis on the metabolites found in the surface ocean. Using seawat...
2017-05-23 | MTBLS461 | MetaboLights
MetabolomicsOrganic sulfur: a spatially variable, labile, and understudied component of marine organic matter

Sulfur (S) is a major heteroatom in organic matter. This project evaluated spatial variability in the concentration and molecular-level composition of organic sulfur along gradients of depth and latitude. We measured the concentration of total organic sulfur (TOS) directly from whole seawater. Ou...

2019-11-12 | MTBLS1024 | MetaboLights
ProteomicsP4PP: an universal shotgun proteomics data analysis pipeline for virus identification, samples of DGA CBRN Defence Center
Humans can be infected by a wide variety of virus species. To detect these different viruses, a data analysis approach for shotgun proteomic data was developed. For this proteome for pandemic preparedness (P4PP) pipeline, a database (P4PPv01) and a web application (P4PP) were constructed. The P4PP p...
ORGANISM(S): Pixuna virus Cercopithecus aethiops (Green monkey) (Grivet) Rio Negro virus Sindbis virus 
2025-06-06 | PXD057670 | Pride
Virus Identification Lc-ms/ms 
MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
TranscriptomicsTaura Syndrome Virus or Yellow Head Virus infection in two strains of L. vannamei different in their resistance to TSV
The transcriptomic response of two strains of the Pacific whiteleg shrimp, different in their resistance to Taura Syndrome Virus (TSV), in response to infection with TSV and Yellow Head Virus (YHV). Changes in gene expression in the shrimp’s hepatopancreas were assessed using a cDNA microarray conta...
ORGANISM(S): Litopenaeus vannamei 
2009-10-23 | E-GEOD-13354 | biostudies-arrayexpress
MetabolomicsViral infection of algal blooms leaves a unique metabolic footprint on the dissolved organic matter in the ocean

Algal blooms are hotspots of primary production in the ocean, forming the basis of the marine food web and fueling the dissolved organic matter (DOM) pool. Marine viruses are key players in controlling algal bloom demise, thereby diverting algal biomass from higher trophic levels to the DOM pool,...

2021-05-05 | MTBLS1720 | MetaboLights
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