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MetabolomicsChemotherapy Modulation by a Cancer-Associated Microbiota Metabolite (Targeted metabolomics - 2methylisocitrate)

Understanding how the microbiota produces regulatory metabolites is of significance for cancer and cancer therapy. Using a host-microbe-drug-nutrient 4-way screening approach, we evaluated the role of nutrition at the molecular level in the context of 5-fluorouracil toxicity. Notably, our screens...

2025-09-16 | MTBLS9994 | MetaboLights
MetabolomicsChemotherapy Modulation by a Cancer-Associated Microbiota Metabolite (Targeted metabolomics - fluoronucleotides)

Understanding how the microbiota produces regulatory metabolites is of significance for cancer and cancer therapy. Using a host-microbe-drug-nutrient 4-way screening approach, we evaluated the role of nutrition at the molecular level in the context of 5-fluorouracil toxicity. Notably, our screens...

2025-09-16 | MTBLS9991 | MetaboLights
MetabolomicsGNPS - The nutritional and host environment shapes community ecology and keystone functions in a synthetic gut bacterial community
Microbe-microbe interactions are critical for gut microbiome function. A challenging task to understand health and disease-related microbiome signatures is to move beyond descriptive community-level profiling towards disentangling microbial interaction networks. Here, we aimed to determine members t...
ORGANISM(S): Bacteria (ncbitaxon:2) Mus Sp. (ncbitaxon:10095) 
2022-11-14 | MSV000090704 | GNPS
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