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ProteomicsAn optimized and robust workflow for quantifying the canonical histone ubiquitination marks H2AK119ub and H2BK120ub by LC-MS/MS
The eukaryotic genome is packaged around histone proteins, which are subject to a myriad of post-translational modifications. By controlling DNA accessibility and the recruitment of protein complexes that mediate chromatin-related processes, these modifications constitute a key mechanism of epigenet...
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-12-10 | PXD053212 | panorama
GenomicsTDRD3 is an effector molecule for arginine methylated histone marks
Specific sites of histone tail methylation are associated with transcriptional activity at gene loci. These methyl-marks are interpreted by effector molecules, which harbor protein domains that bind the methylated motifs and facilitate either active or inactive states of transcription. CARM1 and PRM...
ORGANISM(S): Homo sapiens 
2011-01-06 | E-GEOD-22612 | biostudies-arrayexpress
GenomicsIdentification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
We report the identification of 67 previously undescribed histone modifications, increasing the current number of known histone marks by about 70%. We further investigated one of the marks, lysine crotonylation (Kcr), confirming that it represents an evolutionarily-conserved histone posttranslationa...
ORGANISM(S): Mus musculus 
2011-10-06 | E-GEOD-32663 | biostudies-arrayexpress
GenomicsImpact of Tcf1 and Lef1 deficiency on histone marks and Tcf1 binding in CD8 T cells
Comparison of epigenome and Tcf1 occupancy between control and Tcf1/Lef1-deficient CD8 T cells Control mice or those are deficient for Tcf1 and Lef1 transcription factors (deleted by CD4-Cre) were used to isolate thymocytes. The thymocytes were surface-stained to identify TCRbeta high, CD69–, CD24...
ORGANISM(S): Mus musculus 
2016-02-12 | E-GEOD-73239 | biostudies-arrayexpress
ProteomicsReader interactome of epigenetic histone marks in birds
Lysine methylation is part of the posttranscriptional histone code employed to recruit modification specific readers to chromatin. Unbiased, quantitative mass spectrometry approaches combined with peptide pull-downs have been used to study histone methylation-dependent binders in mammalian cells. He...
ORGANISM(S): Gallus gallus (Chicken) Taeniopygia guttata (Zebra finch) (Poephila guttata) 
2016-01-04 | PXD002282 | Pride
Histone Birds Lc-msms Interactome 
TranscriptomicsCrosstalk between gene body DNA methylation, H3K9me3 and H3K36me3 chromatin marks and transcription [HuGene-1_0-st]
This is one of expressional parts of the study. These data were correlated to epigenetic marks and CG density of genes in analyzed cells. The whole study has a following summary: To elucidate possible roles of DNA methylation and chromatin marks in transcription, we performed epigenetic profiling of...
ORGANISM(S): Homo sapiens 
2011-03-31 | E-GEOD-26019 | biostudies-arrayexpress
ProteomicsScentmarking communication in the female rat_C4PR_LIV
Chemical communication in mammals is in part mediated through the deposition of scent marks in the environment. Volatile and non-volatile moleculesin the scent marksconvey important information about the donor animal, such as sex, social and reproductive status,and stimulatea response in the recepto...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-05-29 | PXD039325 | Pride
Scents Mups Norway rat 
GenomicsBivalent Chromatin Marks Developmental Regulatory Genes in the Mouse Embryonic Germline in Vivo
We developed a ChIP protocol for the analysis of histone marks using less than 10,000 cells per IP, and used it to investigate the chromatin state of E11.5 mouse primordial germ cells (PGCs). A genome-wide ChIP-Seq analysis of E11.5 PGCs revealed a distribution of H3K4me3/H3K27me3 bivalent domains h...
ORGANISM(S): Mus musculus 
2013-05-30 | E-GEOD-46396 | biostudies-arrayexpress
UnknownDistinguishing butchery cut marks from crocodile bite marks through machine learning methods.
Not available
S-EPMC5893542 | biostudies-literature
GenomicsChrom-seq Identifies RNAs at Chromatin Marks [Chrom_and_RNA_seq]
Chrom-seq Identifies RNAs at Chromatin Marks [Chrom_and_RNA_seq]
PRJNA1062749 | ENA
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