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TranscriptomicsTranscription profiling of Arabidopsis defective in the expression of TGA2, TGA5, and TGA6
12-oxo-phytodienoic acid (OPDA) and phytoprostane A1 (PPA1) are cyclopentenone oxylipins that are formed via the enzymatic; jasmonate pathway and a nonenzymatic, free radical–catalyzed pathway, respectively. Both types of cyclopentenone oxylipins; induce the expression of genes related to detoxifi...
ORGANISM(S): Arabidopsis thaliana 
2008-06-18 | E-GEOD-10732 | biostudies-arrayexpress
TranscriptomicsResponse of Arabidopsis cell culture to phytoprostane A1
12-Oxo-phytodienoic acid (OPDA) and several phytoprostanes are structurally related cyclopentenone oxylipins that can be formed via the enzymatic jasmonate pathway and a non-enzymatic, free radical-catalyzed pathway, respectively. To elucidate the biological activities of phytoprostanes in compariso...
ORGANISM(S): Arabidopsis thaliana 
2008-06-18 | E-GEOD-10719 | biostudies-arrayexpress
TranscriptomicsLAA expression profiles on LSC compared to other tissues
Leukemic stem cells (LSC) might be the source for leukemic disease self-renewal and account for disease relapse after treatment, which makes them a critical target for further therapeutic options. Leukemia associated antigens (LAA) might be suitable structures to be attacked by immunotherapeutic age...
ORGANISM(S): Homo sapiens 
2015-04-23 | E-GEOD-68172 | biostudies-arrayexpress
TranscriptomicsAnalysis of the CcpA regulon in Staphylococcus aureus
Background The catabolite control protein A (CcpA) is a member of the LacI/GalR family of transcriptional regulators controlling carbon-metabolism pathways in low-GC Gram positive bacteria. It functions as a catabolite repressor or activator, allowing the bacteria to utilize the preferred carbon sou...
ORGANISM(S): Staphylococcus aureus subsp. aureus str. Newman 
2010-06-24 | E-GEOD-12614 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver from wild type and Hfe-/- mice with hereditary hemochromatosis subjected to dietary iron overload and treatment with nifedipine to reverse iron overload
Hereditary hemochromatosis and transfusional iron overload are frequent clinical conditions associated with progressive iron accumulation in parenchymal tissues leading to eventual organ failure. We have discovered a novel mechanism to reverse iron overload by pharmacological modulation of the dival...
ORGANISM(S): Mus musculus 
2007-03-01 | E-MEXP-982 | biostudies-arrayexpress
TranscriptomicsTCDD induced gene expression changes in dendritic cells
Effect of the over activation of the aryl hydrocarbon receptor on gene expression of spleen derived dendritic cells. 8-12 week old, female C57BL6 mice were injected 10 µg/kg TCDD i.p. or solvent control. After 24 h mice were sacrificed and splenic dendritic cells purified by MACS sorting.
ORGANISM(S): Mus musculus 
2008-11-25 | E-GEOD-13719 | biostudies-arrayexpress
GenomicsGlioma exome array DAC
Data Access Committee EGAC00001000345
EGAC00001000345 | EGA
TranscriptomicsGene expression profiles of human immature dendritic cells after 3h, 6h and 12h of co-cultivation with Aspergillus fumigatus
Gene expression profiles of human immature dendritic cells after 3h, 6h, 9h and 12h of co-cultivation with Aspergillus fumigatus were compared to expression profiles from human immature dendritic cells after 3h, 6h, 9h and 12h of cultivation. We used microarrays to detail the gene expression of huma...
ORGANISM(S): Homo sapiens 
2011-03-29 | E-GEOD-21353 | biostudies-arrayexpress
UnknownAnnexin A5 controls VDAC1-dependent mitochondrial Ca2+ homeostasis and determines cellular susceptibility to apoptosis
Not available
S-SCDT-10_1038-S44318-025-00454-9 | biostudies-other
TranscriptomicsA MYC-driven change in mitochondrial dynamics limits stem cell properties of mammary epithelial cells (RNA-seq)
In several developmental lineages, an increase in expression of the MYC proto-oncogene drives the transition from quiescent stem cells to transit amplifying cells. The mechanism by which MYC restricts self-renewal of adult stem cells is unknown. Here, we show that MYC activates a stereotypic transcr...
ORGANISM(S): Homo sapiens 
2015-10-28 | E-GEOD-66250 | biostudies-arrayexpress
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