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UnknownSequencing Strategies to Guide Decision Making in Cancer Treatment.
Not available
S-EPMC5140043 | biostudies-literature
UnknownMicroRNA Expression-Based Model Indicates Event-Free Survival in Pediatric Acute Myeloid Leukemia.
Not available
S-EPMC5721230 | biostudies-literature
TranscriptomicsLNCaP Atlas: Gene expression associated with in vivo progression to castration-recurrent prostate cancer
Background: There is no cure for castration-recurrent prostate cancer (CRPC) and the mechanisms underlying this stage of the disease are unknown. Methods: We analyzed the transcriptome of human LNCaP prostate cancer cells as they progress to CRPC in vivo using replicate LongSAGE libraries. We refer ...
ORGANISM(S): Homo sapiens 
2010-09-26 | E-GEOD-18402 | biostudies-arrayexpress
TranscriptomicsEffect of TERT and ATM on Gene Expression Profiles in Human Fibroblasts
Gene expression profiling was performed by use of serial analysis of gene expression (SAGE) on BJ normal human skin fibroblasts, A-T cells, and BJ and A-T cells transduced with hTERT cDNA and expressing telomerase activity. Keywords = telomere Keywords = telomerase Keywords = TERT Keywords = ataxia ...
ORGANISM(S): Homo sapiens 
2004-01-16 | E-GEOD-953 | biostudies-arrayexpress
TranscriptomicsIdentification of novel androgen-responsive genes by sequencing of LongSAGE libraries
Background: The development and maintenance of the prostate is dependent on androgens and the androgen receptor. The androgen pathway continues to be important in prostate cancer. Here, we evaluated the transcriptome of prostate cancer cells in response to androgen using long serial analysis of gene...
ORGANISM(S): Homo sapiens 
2009-10-20 | E-GEOD-18401 | biostudies-arrayexpress
GenomicsA somatic reference standard for cancer genome sequencing with COLO829
Identification of somatic alterations in cancer has become feasible with the massive adoption of next generation sequencing. However, due to variability in sequencing and informatics pipelines, a common somatic reference is needed. We thus performed paired whole genome sequencing of a metastatic mel...
EGAS00001001385 | EGA
TranscriptomicsSAGE Libraries from Highly Purified Mouse Hematopoietic Stem Cells from the E14.5 Fetal Liver and Adult Bone Marrow
Recent improvements in the development of methods for isolating functionally validated populations of nearly pure (>20%) murine hematopoietic stem cells (HSCs) have made it possible to analyze the molecular basis of the properties of these cells with increased precision. One intriguing feature of HS...
ORGANISM(S): Mus musculus 
2008-10-18 | E-GEOD-13243 | biostudies-arrayexpress
TranscriptomicsC. elegans SAGE
The SAGE libraries were built from total mRNA populations in specific tissues, cells, mutation-specific populations, and all developmental stages of C. elegans. Tissue- and cell-specific libraries were generated from FACS-sorted cells marked by expression of specific promoter::GFP fusions Keywords ...
ORGANISM(S): Caenorhabditis elegans 
2004-06-11 | E-GEOD-1447 | biostudies-arrayexpress
Genomicsena-DATASET-TGEN-24-05-2016-20:32:03:406-20 - samples
Paired PCR-free whole genome sequencing data of a matched metastatic melanoma cell line (COLO829) and normal across three lineages and across separate institutions, with independent library preparations, sequencing, and analysis. The data was generated with mean mapped coverages of 99X for COLO829 a...
EGAD00001002142 | EGA
GenomicsCharbonneau Cancer Institute DAC
Data Access Committee EGAC00001001280
EGAC00001001280 | EGA
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