Sort   by:  
 Page size 
ProteomicsSystematic Discovery of Pro- and Anti-HIV Host Factors in Primary Human CD4+ T Cells
Despite extensive efforts, significant gaps remain in our understanding of which host factors promote or restrict human immunodeficiency virus (HIV) infection in human CD4+ T cells. Here, we employed orthogonal genome-wide CRISPR activation (CRISPRa) and CRISPR knockout (CRISPRn) screens in primary ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD071892 | Pride
Host factor Ip-ms Ppi Pi16 Hiv Cd4+ t cells 
GenomicsChIP-seq analysis of histone modifications and RNA polymerase II at 4 stages of directed cardiac differentiation of mouse embryonic stem cells
We interrogated the genome-wide occupancy of histone modifications and RNA polymerase II at several stages of an mouse embryonic stem cell to cardiomyocyte directed differentiation protocol. These four stages represent timepoints when differentiating cultures are enriched for embryonic stem cells (...
ORGANISM(S): Mus musculus 
2013-06-15 | E-GEOD-47949 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Oct4, Nanog and Suz12 in human and mouse embryonic stem cells to identify promoters for miRNAs
Understanding the transcriptional regulatory circuitry responsible for pluripotency and self-renewal in embryonic stem (ES) cells is fundamental to understanding human development and realizing the therapeutic potential of these cells. The transcription factor Oct4 and the chromatin-modifying Polyc...
ORGANISM(S): Homo sapiens 
2010-12-01 | E-TABM-365 | biostudies-arrayexpress
ProteomicsARIH2 is a novel Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection
Discovery of novel host-virus interactions leads to a better understanding of mechanisms underlying infection and points to potential therapeutic targets at the interface between virus and host proteins. Recently, global, virus-host interaction networks have been mapped using affinity purification-m...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-29 | MSV000084855 | MassIVE
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM_CBFB_CUL2_CUL5_interactors
SRM assays were generated for selected interactors of CUL5, CBFB and ELOB. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated fro...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084965 | MassIVE
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM-CBFB
SRM assays were generated for selected interactors of CBFB. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated from the shotgun M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084964 | MassIVE
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM-ELOB
SRM assays were generated for selected interactors of ELOB. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated from the shotgun M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084962 | MassIVE
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM-CUL5
SRM assays were generated for selected interactors of CUL5. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated from the shotgun M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084963 | MassIVE
GenomicsRASA2 checkpoint ablation in T cells boosts antigen sensitivity and long-term function
RASA2 checkpoint ablation in T cells boosts antigen sensitivity and long-term function
PRJNA842576 | ENA
GenomicsPOKI-Seq in Primary Human T Cells
POKI-Seq in Primary Human T Cells
PRJNA600416 | ENA
Sort   by:  
 Page size