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TranscriptomicsAnalysis of the transcriptional response to bleomycin-induced DNA damage in Physcomitrella patens wild type and mutants defective in the ATM, ATR genes and the double mutant
To analyse the early phase of the transcriptional response to bleomycin-induced damage and its dependence on the severity of the damage, we used exposure for 1 hour to a sub-lethal (0.3 u/l) and a lethal (3 u/l) dose of bleomycin. In addition, an aliquot of the 0.3 u/l treatment was washed free of b...
ORGANISM(S): Physcomitrella patens 
2020-05-04 | E-MTAB-9082 | biostudies-arrayexpress
TranscriptomicsGlycan effect on Saccharolytic Human Distal Gut Symbiont, B. thetaiotaomicron
This SuperSeries is composed of the following subset Series: GSE11944: Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont GSE11953: Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont: ECF ...
ORGANISM(S): Bacteroides thetaiotaomicron 
2008-11-20 | E-GEOD-11980 | biostudies-arrayexpress
TranscriptomicsMucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont: ECF mutant
Growth of isogenic parent ('tdk strain'), 5xECF-sigma factor mutant and complemented mutant strain in the cecum of NMRI inbred mice fed a glycan-restricted, 'simple sugar' diet (35% each glucose and sucrose). Bacteria were collected from mouse distal gut 10 days after colonization. Experiment perfor...
ORGANISM(S): Bacteroides thetaiotaomicron 
2008-11-20 | E-GEOD-11953 | biostudies-arrayexpress
TranscriptomicsMucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont
Gene expression profiles of Bacteroides thetaiotaomicron in vitro during growth on host mucosal polysaccharides as sole carbon sources. All substrates in this series are derived from porcine gastric mucin and include mucin O-glycans and glycosaminoglycans. Two different culture formats used: 800ml b...
ORGANISM(S): Bacteroides thetaiotaomicron 
2008-11-20 | E-GEOD-11944 | biostudies-arrayexpress
TranscriptomicsCoordinate regulation of glycan degradation and polysaccharide capsule biosynthesis by a prominent human gut symbiont
Analysis of B. thetaiotaomicron trans-envelope signaling mutants in ECF-sigma factors, anti-sigma factors and SusC-like transporters. B. thetaiotaomicron mutants were transcriptionally profiled after growth in vitro in either minimal medium plus glucose or minimal medium plus neutral O-glycans
ORGANISM(S): Bacteroides thetaiotaomicron VPI-5482 
2010-05-18 | E-GEOD-14592 | biostudies-arrayexpress
MetabolomicsMono-Locus and Pyramided Resistant Grapevine Cultivars Reveal Early Putative Biomarkers Upon Artificial Inoculation With Plasmopara viticola
One of the most economically important grapevine diseases is Downy mildew (DM) caused by the oomycete Plasmopara viticola. A strategy to reduce the use of fungicides to compensate for the high susceptibility of V. vinifera is the selection of grapevine varieties showing pathogen-specif...
2021-07-07 | MTBLS2876 | MetaboLights
TranscriptomicsGrowth of B. thetaiotaomicron on purified host mucosal glycans and glycan fragments
Bacteroides thetaiotaomicron was grown and transcriptionally profiled on a number of different host mucosal glycans and their component mono- and disaccharides. Experiments are performed in biological duplicate (2 replicates per growth condition). All cultures were harvested at similar points in mid...
ORGANISM(S): Bacteroides thetaiotaomicron 
2008-11-20 | E-GEOD-11962 | biostudies-arrayexpress
MetabolomicsPROMIS, global analysis of PROtein-Metabolite Interactions using Size separation in Arabidopsis thaliana
Small molecules not only represent cellular building blocks and metabolic intermediates, but also regulatory ligands and signaling molecules that interact with proteins. Although these interactions affect cellular metabolism, growth, and development, they have been largely understudied. Herein, we d...
2018-07-19 | MTBLS94 | MetaboLights
UnknownEffects on transcriptional regulation and lipid droplet characteristics in the liver of female juvenile pigs after early postnatal feed restriction and refeeding are dependent on birth weight.
Not available
S-EPMC3834034 | biostudies-literature
UnknownParameter estimation in biochemical systems models with alternating regression.
Not available
S-EPMC1586003 | biostudies-literature
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