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TranscriptomicsTranscription profiling of human umbilical vein endothelial cells treated with Interferon-gamma (IFN-g), Borrelia burgdorferi or both IFN-g and Borrelia or untreated to investigate immune responses to Lyme disease
Borrelia burgdorferi, the agent of Lyme disease, promotes pro-inflammatory changes in endothelium that lead to the recruitment of leukocytes. The host immune response to infection results in increased levels of IFN-gamma in the serum and lesions of Lyme disease patients that correlate with greater s...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6092 | biostudies-arrayexpress
TranscriptomicsGenome-wide blood DNA methylation levels in MARTHA participants
The goal of this study was to identify whole blood DNA methylation marks associated with biomarkers characterizing the Thrombin Generation Potential. Dataset includes 238 samples from MARTHA study (MARseille THrombosis Association Study) epityped for the Illumina HumanMethylation 450K and phenotype...
ORGANISM(S): Homo sapiens 
2014-12-15 | E-MTAB-3127 | biostudies-arrayexpress
UnknownSalmonella Promotes Its Own Survival in B Cells by Inhibiting Autophagy.
Not available
S-EPMC9266210 | biostudies-literature
UnknownOral immunization of mice with gamma-irradiated Brucella neotomae induces protection against intraperitoneal and intranasal challenge with virulent B. abortus 2308.
Not available
S-EPMC4166413 | biostudies-literature
UnknownIntensity of CD23 expression on IgG<sub>1</sub> <sup>+</sup> B cells reflects serum IgE level in asthma.
Not available
S-EPMC12465039 | biostudies-literature
TranscriptomicsComparison of B-MSCs from young and old mice
Total RNA of B-MSCs from young and old mice were compared using Agilent microarrays. Bone marrow cells from old and young mice were labeled and sorted.
ORGANISM(S): Mus musculus 
2014-02-18 | E-GEOD-44403 | biostudies-arrayexpress
GenomicsEstablishment of Enhancer Repertoires that Orchestrate the Myeloid and Lymphoid Cell Fates (ChIP-Seq dataset)
Recent studies have documented genome-wide binding patterns of transcriptional regulators and their associated epigenetic marks in hematopoietic cell lineages. In order to determine how epigenetic marks are established and maintained during developmental progression, we have generated long-term cult...
ORGANISM(S): Mus musculus 
2011-09-01 | E-GEOD-30858 | biostudies-arrayexpress
GenomicsThe NF-kB genomic landscape in lymphoblastoid B-cells
The nuclear factor kB (NF-kB) subunits RelA, RelB, c-Rel, p50 and p52 are each critical for B-cell development and function. To systematically characterize their responses to canonical and non-canonical NF-kB pathways activity, we performed ChIP-seq analysis in lymphoblastoid B-cells. We found a su...
ORGANISM(S): Homo sapiens 
2014-08-29 | E-GEOD-55105 | biostudies-arrayexpress
UnknownEpstein-Barr Virus-Induced Genes and Endogenous Retroviruses in Immortalized B Cells from Patients with Multiple Sclerosis.
Not available
S-EPMC9688211 | biostudies-literature
UnknownA randomized feasibility trial of the Midlife Black Women's Stress and Wellness intervention (B-SWELL); a community participatory intervention to increase adoption of Life's Simple 7 healthy lifestyle behaviors.
Not available
S-EPMC9677463 | biostudies-literature
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