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ProteomicsAn organ-specific angiogenic control mechanism for endothelial tailoring.
Each organ of the human body requires locally-adapted blood vessels1–3. The gain of such organotypic vessel specializations is often deemed molecularly unrelated to the process of organ vascularization. Opposing this model, we reveal a molecular mechanism for brain-specific angiogenesis that operate...
ORGANISM(S): Homo sapiens (Human) 
2024-02-08 | PXD042613 | Pride
Angiogenesis  tip cell angiodiversity  wnt/β-catenin signaling  blood-brain barrier  bbb  mmp25  col4a5  col4a6  pial fibroblast  gpr124  reck  wnt7a 
TranscriptomicsRegulation of ER Homeostasis and Cell Cycle by Pax4 Enhances β-Cell Survival and Protects Mice Against Experimental Autoimmune Diabetes
Strategies to enhance islet b-cell survival and regeneration while refraining inflammation through manipulation of molecular targets would provide means to stably replenish the deteriorating functional b-cell mass detected in both Type 1 and Type 2 Diabetes Mellitus (T1DM and T2DM). Herein we report...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-62846 | biostudies-arrayexpress
MetabolomicsMetabolomic signatures discriminate horses with clinical signs of atypical myopathy from healthy co-grazing horses
Atypical myopathy (AM) is a severe rhabdomyolysis syndrome that occurs in grazing horses. Despite the presence of toxins in their blood, all horses from the same pasture are not prone to display clinical signs of AM. The objective of this study was to compare the blood metabolomic profiles of horses...
2021-08-31 | MTBLS2579 | MetaboLights
UnknownChildhood Acute Lymphoblastic Leukemia: Progress Through Collaboration.
Not available
S-EPMC4567699 | biostudies-literature
UnknownInfluenza Vaccine Effectiveness in the United States during the 2015-2016 Season.
Not available
S-EPMC5727917 | biostudies-literature
UnknownExploratory Study on Application of MALDI-TOF-MS to Detect SARS-CoV-2 Infection in Human Saliva.
Not available
S-EPMC8781148 | biostudies-literature
UnknownThe International Classification of Functioning, Disability and Health Core Set for deafblindness. Part I: a systematic review of outcome measures.
Not available
S-EPMC10664768 | biostudies-literature
ProteomicsAlterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by multi-omic analysis
Background Alterations of the gut microbiome have been linked to multiple chronic diseases. However, the drivers of such changes remain largely unknown. The oral cavity acts as a major route of exposure to exogenous factors including pathogens, and processes therein may affect the communities in the...
ORGANISM(S): human metagenome 
2022-10-05 | PXD031579 | Pride
Microbiome   metaproteomics   type 1 diabetes 
MetabolomicsEvaluation of sample preparation methods for NMR-based metabolomics of cow milk
The quality of milk metabolome analyzed by nuclear magnetic resonance (NMR) is greatly influenced by the way samples are prepared. Although this analytical method is increasingly used to study milk metabolites, a thorough examination of available sample preparation protocols for milk has not been re...
2019-06-13 | MTBLS623 | MetaboLights
UnknownFull-field optical coherence tomography for the diagnosis of giant cell arteritis.
Not available
S-EPMC7458309 | biostudies-literature
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