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TranscriptomicsB-cell tumor development in Tet2-deficient mice
The TET2 gene encodes an α-ketoglutarate-dependent dioxygenase able to oxidize 5-methylcytosine into 5-hydroxymethylcytosine, which is a step toward active DNA demethylation. TET2 is frequently mutated in myeloid malignancies but also in B- and T-cell malignancies. TET2 somatic mutations are also id...
ORGANISM(S): Mus musculus 
2019-12-12 | E-MTAB-8501 | biostudies-arrayexpress
UnknownLentiviral gene therapy reverts GPIX expression and phenotype in Bernard-Soulier syndrome type C.
Not available
S-EPMC10320622 | biostudies-literature
UnknownB-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity.
Not available
S-EPMC3375897 | biostudies-literature
UnknownCore enhancers of the 3'RR optimize IgH nuclear position and loop conformation for successful oriented class switch recombination.
Not available
S-EPMC11551739 | biostudies-literature
TranscriptomicsNotch targets in KC Drosophila cells
To identify genes upregulated in response to Notch signalling in KC cells. Keywords: Expression analysis at a single timepoint (30' after Notch activation) KC cells were obtained from Dr Martin Zeidler. Control versus Notch activated KC cells: mRNA was extracted from KC cells incubated in the absenc...
ORGANISM(S): Drosophila melanogaster 
2010-06-23 | E-GEOD-9965 | biostudies-arrayexpress
UnknownEpigenetic features support the diagnosis of B-cell prolymphocytic leukemia and identify 2 clinicobiological subtypes.
Not available
S-EPMC11700275 | biostudies-literature
TranscriptomicsHelin-Human-HH9si
Gene expression in HeLa cells was monitored after interference for HectH9
ORGANISM(S): Homo sapiens 
2005-10-17 | E-MEXP-408 | biostudies-arrayexpress
UnknownTET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Not available
S-EPMC6279514 | biostudies-literature
UnknownPrognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal A breast cancer.
Not available
S-EPMC3532392 | biostudies-literature
UnknownWhat does social participation mean? A qualitative study exploring the concept of participation from the perspectives of experts and parents.
Not available
S-EPMC10351295 | biostudies-literature
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