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UnknownDiffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis.
Not available
S-EPMC4397280 | biostudies-literature
UnknownEfficacy and Safety of Nivolumab Alone or in Combination With Ipilimumab in Patients With Mucosal Melanoma: A Pooled Analysis.
Not available
S-EPMC5559888 | biostudies-literature
TranscriptomicsGene expression profiles of normal B-cell subsets from sternal bone marrow
Mononuclear cells were isolated from the sternal bone marrow and prepared for multiparametric flow cytometry using an optimized and validated protocol. B-cell subsets of PreBI, PreBII, Immature, Naive, Memory and Plasma cells were isolated and a al of 38 gene expression profiles were generated using...
ORGANISM(S): Homo sapiens 
2016-02-09 | E-GEOD-68878 | biostudies-arrayexpress
TranscriptomicsResveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on a high-fat, high-sugar diet.
Obesity is associated with a chronic, low-grade, systemic inflammation that may contribute to the development of insulin resistance and type 2 diabetes. Resveratrol, a natural compound with anti-inflammatory properties, is shown to improve glucose tolerance and insulin sensitivity in obese mice and ...
ORGANISM(S): Macaca mulatta 
2014-04-21 | E-GEOD-50005 | biostudies-arrayexpress
TranscriptomicsLong noncoding RNA expression during human B-cell development
Long noncoding RNAs (lncRNAs) have emerged as important regulators of diverse cellular processes, but their roles in the developing immune system are poorly understood. In this study, we analysed lncRNA expression during human B-cell development by array-based expression profiling of eleven distinct...
ORGANISM(S): Homo sapiens 
2016-02-09 | E-GEOD-69033 | biostudies-arrayexpress
GenomicsNational Cancer Institute (NCI) TARGET: Therapeutically Applicable Research to Generate Effective Treatments

The Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative seeks to accelerate research in novel marker and drug development, along with understanding the molecular basis of pediatric malignancy, through identification of genomic changes associated with the follo...

phs000218.v5.p1 | EGA
GenomicsSCLC_SNP_6.0 - samples
SNP 6.0 arrays of small cell lung cancer
EGAD00010000558 | EGA
Genomicsena-DATASET-RTL-11-03-2015-12:07:49:303-16 - samples
Whole genome sequencing was performed with DNA extracted from fresh-frozen tumor and normal material. Short insert DNA libraries were prepared with the TruSeq DNA PCRfree sample preparation kit (Illumina) for paired-end sequencing at a minimum read length of 2x100bp. Human DNA libraries were sequenc...
EGAD00001001273 | EGA
Genomicsena-DATASET-RTL-06-02-2015-14:59:15:066-180 - samples
RNA-sequencing (RNA-seq) was performed with RNA extracted from fresh-frozen human tumor tissue samples. cDNA libraries were prepared from poly-A selected RNA applying the Illumina TruSeq protocol for mRNA. The libraries were then sequenced with a 2 x 100bp paired-end protocol to a minimum mean cover...
EGAD00001001244 | EGA
GenomicsComprehensive genomic profiles of small cell lung cancer
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. We found bi-allelic inactivation of TP53 and RB1 in nearly all the tumors analyzed, sometimes by complex genomic rearrangements. Two tumors with wild-type RB1 had evidence of chromothripsis leadi...
EGAS00001000925 | EGA
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