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no omics definedChromatin immunoprecipitation of ATF3-/- mouse bone marrow macrophages with and without stimulation with lipopolysaccharide for 1 or 2 hours
DNA binding determination for ATF3 -/- macrophages without stimulation and with stimulation by LPS after 1 or 2 hours.
ORGANISM(S): Mus musculus 
2006-07-07 | E-MEXP-730 | biostudies-arrayexpress
TranscriptomicsEstrogens and selective estrogen receptor modulators regulate gene and protein expression in the mesenteric arteries
Estrogen is a reproductive steroid hormone that has both beneficial and detrimental effects on the cardiovascular system. Selective estrogen receptor modulators (SERMs) exhibit partial estrogen agonist/antagonist activity in estrogen target tissues. Since we still have an incomplete picture of the ...
ORGANISM(S): Rattus norvegicus 
2011-07-06 | E-GEOD-23037 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis to assess spiking
Transcript profiling is crucial to study biological systems and various platforms have been implemented to survey mRNAs at the genome scale. We have assessed the characteristics of the CATMA microarray designed for Arabidopsis thaliana transcriptome analysis, and compared it with two commercial plat...
ORGANISM(S): Arabidopsis thaliana 
2004-11-23 | E-MEXP-197 | biostudies-arrayexpress
TranscriptomicsThe bile acid CoA ligase, FATP5, is necessary for NAT synthesis in the liver
This study aimed to investigate the overlap between hepatic NAT and the bile acid synthesis to identify additional enzymes involved in NAT synthesis in the liver. We sequenced livers high-fat fed mice the were either wild-type or with a single-amino acid substitution in fatty acid amide hydrolase (F...
ORGANISM(S): Mus musculus 
2026-03-02 | E-MTAB-15752 | biostudies-arrayexpress
ProteomicsStable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant
We explore the possibility of re-engineering mitochondrial genes and expressing them from the nucleus as an approach to rescue defects arising from mitochondrial DNA mutations. We have used a patient cybrid cell line with a single point mutation in the overlap region of the ATP8 and ATP6 genes of th...
ORGANISM(S): Homo Sapiens (human) 
2016-08-12 | MSV000080037 | MassIVE
TranscriptomicsTranscription profiling of Arabidopsis mutants (elo2, elo3, drl1-2 and ang4) vs the wild type Ler strain
Microarray transcript profiling and RNA interference are two new technologies crucial for large-scale gene function studies in multicellular eukaryotes. Both rely on sequence-specific hybridization between complementary nucleic acid strands, inciting us to create a collection of gene-specific sequen...
ORGANISM(S): Arabidopsis thaliana 
2004-05-07 | E-MEXP-30 | biostudies-arrayexpress
UnknownGlobal, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
Not available
S-EPMC6227755 | biostudies-literature
GenomicsBP_August_2016_RNA-Seq_hematopoietic_multipotent_progenitor_cell_on_GRCh38 - samples
RNA-Seq data for 3 hematopoietic multipotent progenitor cell sample(s). 9 run(s), 3 experiment(s), 3 analysis(s) on human genome GRCh38. Part of BLUEPRINT release August 2016. Analysis documentation available at http://ftp.ebi.ac.uk/pub/databases/blueprint/releases/20160816/homo_sapiens/README_rnase...
EGAD00001002363 | EGA
GenomicsBP_January_2015_RNA-Seq_CD34-negative,_CD41-positive,_CD42-positive_megakaryocyte_cell - samples
RNA-Seq data for 5 CD34-negative, CD41-positive, CD42-positive megakaryocyte cell sample(s). 23 run(s), 5 experiment(s), 5 alignment(s). Part of BLUEPRINT release January 2015. Analysis documentation available at http://ftp.ebi.ac.uk/pub/databases/blueprint/releases/20140811/homo_sapiens/README_rnas...
EGAD00001001165 | EGA
GenomicsBP_August_2015_RNA-Seq_granulocyte_monocyte_progenitor_cell_on_GRCh38 - samples
RNA-Seq data for 3 granulocyte monocyte progenitor cell sample(s). 3 run(s), 3 experiment(s), 3 alignment(s) on human genome GRCh38. Part of BLUEPRINT release August 2015. Analysis documentation available at http://ftp.ebi.ac.uk/pub/databases/blueprint/releases/20150820/homo_sapiens/README_rnaseq_an...
EGAD00001001501 | EGA
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