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MetabolomicsSpecific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata
The native diploid tobacco Nicotiana attenuata produces abundant, potent anti-herbivore defense metabolites known as 17-hydroxygeranyllinalool diterpene glycosides (HGL-DTGs) whose glycosylation and malonylation biosynthetic steps are regulated by jasmonate signaling. To characterize the biosyntheti...
2021-10-06 | MTBLS1819 | MetaboLights
UnknownADAR-deficiency perturbs the global splicing landscape in mouse tissues.
Not available
S-EPMC7462079 | biostudies-literature
ModelsKavšček2015 - Genome-scale metabolic model of Yarrowia lipolytica (iMK735)
Kavšček2015 - Genome-scale metabolic model of Yarrowia lipolytica (iMK735) This model is described in the article: Optimization of lipid production with a genome-scale model of Yarrowia lipolytica. Kavšček M, Bhutada G, Madl T, Natter K. BMC Syst Biol 2015; 9: 72 Abstrac...
2016-01-20 | MODEL1510060001 | BioModels
TranscriptomicsExpression RNA-Seq data of matched cases of pre-treatment Fine-needle aspiration (FNA) and the respective post neo-adjuvant treatment operative sample of breast cancer patients.
Neoadjuvant treated patients were selected from the Genomstudy of the University Women`s Clinic Heidelberg (2009-2016). This study includes primary breast cancer cases that were newly diagnosed at the University women's clinic of Heidelberg and had given their informed consent for participating in t...
ORGANISM(S): Homo sapiens 
2017-05-15 | E-MTAB-4632 | biostudies-arrayexpress
ProteomicsLandscape of nuclear transport receptor cargo specificity
Nuclear transport receptors (NTRs) recognize localization signals of cargos to facilitate their passage across the central channel of nuclear pore complexes (NPCs). About 30 different NTRs constitute different transport pathways in humans and bind to a multitude of different cargos. The exact cargo ...
ORGANISM(S): Homo sapiens (Human) 
2017-11-14 | PXD007976 | Pride
Proximity ligation Interaction network Protein transport Proteomics Nuclear pore complex 
TranscriptomicsTranscription profiling of human melanoma cell lines
5 melanoma cell lines: MelJUSO, A375, 607B, 518A2, Skmel 28
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1845 | biostudies-arrayexpress
UnknownInterferon regulates neural stem cell function at all ages by orchestrating mTOR and cell cycle.
Not available
S-EPMC10086582 | biostudies-literature
TranscriptomicsLong Non-coding RNA expression profiles in Hereditary Haemorrhagic Telangiectasia
Hereditary Haemorrhagic Telangiectasia (HHT) is an autosomal dominantly inherited vascular disease characterized by the presence of mucocutaneous telangiectasia and arteriovenous malformations in visceral organs. HHT is predominantly caused by mutations in ENG and ACVRL1, Which both belong to the TG...
ORGANISM(S): Homo sapiens 
2014-12-19 | E-GEOD-53515 | biostudies-arrayexpress
Transcriptomicsexpression changes due to constitutive expression of Drosophila miR-277
Drosophila miR-277 is down-regulated during adult life. To infer the transcripts regulated by miR-277, we transgenically expressed the miRNA from a heterologous promotor. RNA was extracted at an age when 50% of the population had died, then we compared the transgenic strain with constitutive express...
ORGANISM(S): Drosophila melanogaster 
2013-11-25 | E-MEXP-3785 | biostudies-arrayexpress
Transcriptomicspulse labeling and fractionation of RNA after inhibition of miR-277 to detect transcriptional and post-transcriptional changes
Drosophila melanogaster Schneider cells (S2) were transfected with a 2'-O-methyl inhibitor antisense to miR-277 or an unrelated control sequence. Three days after inhibition of the miRNA, the cellular RNA was pulse-labeled with 4-thio-Uridine for 1 hour, then tthe cells were lysed and RNA was extrac...
ORGANISM(S): Drosophila melanogaster 
2013-11-25 | E-MEXP-3784 | biostudies-arrayexpress
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