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MetabolomicsAn interoperability framework for multicentric breath metabolomic studies
Exhaled breath contains valuable information at the molecular level and offers promising potential for precision medicine. However, few breath tests transition to routine clinical practice, partly because of the missing validation in multicenter trials. Therefore, we developed and applied an interop...
2022-10-27 | MTBLS5657 | MetaboLights
ModelsBexkens2024 - Schistosoma mansoni glycolysis
A kinetic model of S. mansoni glycolysis in which we can vary the allosteric regulation on lactate dehydrogenase (LDH). Because not enough kinetic data are available for all the schistosome enzymes to construct a complete schistosome glycolysis model de novo, we here adjusted the well-established gl...
2024-04-04 | MODEL2208290002 | BioModels
UnknownWhy does a point of care guided transfusion algorithm not improve blood loss and transfusion practice in patients undergoing high-risk cardiac surgery? A prospective randomized controlled pilot study.
Not available
S-EPMC6379957 | biostudies-literature
UnknownComparative analysis of in-silico tools in identifying pathogenic variants in dominant inherited retinal diseases.
Not available
S-EPMC11102593 | biostudies-literature
TranscriptomicsTranscription profile of dormant and germinating Aspergillus niger conidia
Genome-wide analysis was performed to assess the transcriptional landscape of germinating A. niger conidia using GeneChips. The metabolism of storage compounds during conidial germination was also examined and compared to the transcript levels from associated genes. The transcriptome of dormant coni...
ORGANISM(S): Aspergillus niger 
2013-05-01 | E-GEOD-42480 | biostudies-arrayexpress
UnknownAdding Celecoxib With or Without Zoledronic Acid for Hormone-Naive Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controlled Trial.
Not available
S-EPMC5455701 | biostudies-literature
TranscriptomicsTranscription profiling of human neutrophils obtained after exposure endotoxin by bronchoscopic instillation reveals differential gene expression between air space and circulating neutrophils
Although the accumulation of neutrophils in the lungs and airways is common to many inflammatory lung diseases, including acute lung injury, the alterations that neutrophils undergo as they leave the peripheral circulation and migrate into the lungs have not been well characterized. Human volunteers...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-2322 | biostudies-arrayexpress
TranscriptomicsTrancriptional landscape of Aspergillus niger at breaking of conidial dormancy revealed by RNA-sequencing
Genome-wide analysis was performed to assess the transcriptional landscape of germinating A. niger conidia for first hour using next generation RNA-sequencing. The transcriptome of dormant conidia was shown to be highly differentiated from that of germinating conidia. The breaking of dormancy was as...
ORGANISM(S): Aspergillus niger 
2013-05-01 | E-GEOD-42652 | biostudies-arrayexpress
TranscriptomicsNPMâ??ALK permits the survival of thymic T cells with aberrant T cell receptor rearrangements enabling thymic escape and tumor development
We present evidence to support a new model of Anaplastic Large Cell Lymphoma (ALCL) pathogenesis in which the malignancy is initiated in early thymocytes, prior to TCR rearrangement which is bypassed in NPMâ??ALK transgenic mice following Notch1 expression. In support, we show that T cell receptor (...
ORGANISM(S): Homo sapiens 
2016-01-05 | E-GEOD-67131 | biostudies-arrayexpress
GenomicsNational Cancer Institute (NCI) TARGET: Therapeutically Applicable Research to Generate Effective Treatments

The Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative seeks to accelerate research in novel marker and drug development, along with understanding the molecular basis of pediatric malignancy, through identification of genomic changes associated with the follo...

phs000218.v5.p1 | EGA
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