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TranscriptomicsThe effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis; insights for early bactericidal activity
Background: Pyrazinamide (PZA) plays an essential part in the shortened 6-month tuberculosis (TB) treatment course due to its activity against slow-growing, semi-dormant organisms. We tested the paradigm that PZA preferentially targets slow growing cells of Mycobacterium tuberculosis that remain aft...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2016-03-25 | E-MTAB-4093 | biostudies-arrayexpress
UnknownChanges In Health Services Use After Receipt Of Medications For Opioid Use Disorder In A Statewide Correctional System.
Not available
S-EPMC9036835 | biostudies-literature
ProteomicsA transient protein folding response targets aggregation in the early phase of TDP-43-mediated disease
Understanding the mechanisms that drive TDP-43 pathology is integral to combating amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Here we generated a longitudinal quantitative proteomic map of the cortex from the cytoplasmic TDP-43 rNLS8 mouse model of ALS and FTLD ...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-31 | PXD042382 | Pride
Ftld Longitudinal Als Cortex Mouse Proteinopathy Motor neuron disease Mnd Tdp-43 Lc-ms/ms Tandem mass tagging Amyotrophic lateral sclerosis Frontotemporal dementia Ftd Frontotemporal lobar degeneration 
TranscriptomicsCellular plasticity and diversity during heart valve epithelial-to-mesenchymal transitions revealed using single-cell RNA-seq
We have generated scRNA-seq data from embryonic day (E)10.5 and E12.5 atrioventricular canals (primitive heart valves) to assess cellular diversity during the distinct epithelial-to-mesenchymal transitions (EMTs) from endocardium and epicardium that guide the formation of valve mesenchyme. Alongside...
ORGANISM(S): Mus musculus 
2023-06-30 | E-MTAB-11795 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of brain, liver and spleen from rats infected with Escherichia coli K1 and treated with capsule-selective endosialidase E
Transcription profiling of infected and treated (Capsule-Selective Endosialidase E Minimizes) of RNA isolated from brain/spleen/liver of rats with E.coli K1
ORGANISM(S): Rattus norvegicus 
2010-01-10 | E-MEXP-2406 | biostudies-arrayexpress
UnknownOptic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment.
Not available
S-EPMC3412675 | biostudies-literature
TranscriptomicsTranscription profiling by array of a directed differentiation time course converting human embryonic stem cells (hES) into immature pancreatic beta cell precursors
Transcriptional profiling of a directed differentiation time course converting human embryonic stem cells (hES) into immature pancreatic beta cell precursors.
ORGANISM(S): Homo sapiens 
2012-10-11 | E-MTAB-817 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiling by array of a directed differentiation time course converting human embryonic stem cells (hES) into immature pancreatic beta cell precursors
miRNA transcript profiling of a directed differentiation time course converting human embryonic stem cells (hES) into immature pancreatic beta cell precursors.
ORGANISM(S): Homo sapiens 
2012-10-11 | E-MTAB-818 | biostudies-arrayexpress
GenomicsChIP-Seq of human embryonic stem cells of a differentiation time course with antibody against H3K4me3
H3K4me3 ChIP-Seq profiling of a directed differentiation time course converting human embryonic stem cells (hES) into immature pancreatic beta cell precursors. CyT49, a Viacyte proprietary male hESC line with normal karyotype was used.
ORGANISM(S): Homo sapiens 
2012-10-13 | E-MTAB-821 | biostudies-arrayexpress
TranscriptomicsClr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA (expression)
Expression profile of Schizosaccharomyces pombe genome in ?mlo3, mlo3-A, mlo3-A?h2a.z, ?cid14?h2a.z and mlo3-A?cid14 cells. Expression profile of mutant cells compared to wild-type cells. Agilent 60mer oligonucleotide custom array containing probes spanning large portion of chromosome 2 at 50bp re...
ORGANISM(S): Schizosaccharomyces pombe 
2011-04-12 | E-GEOD-26995 | biostudies-arrayexpress
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