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Exposure to inflammatory cytokines driven by bystander cytokines can have profound effects on the function of memory CD8 T cells. Here we transferred a 1-5X10^4 of P14 TCR-tg T cells (specific for gp33-41 of LCMV) on day -1 followed by infection with 2X10^5 PFU of LCMV Armstrong ip to generate memor...
ORGANISM(S): Mus musculus 
Comparatative gene expression analysis for CD4 T cell subsets isolated from peripheral blood and palatine tonsils
ORGANISM(S): Homo sapiens 
These 95 arrays are the basis for Figure 2 of our manuscript "An interferon-response induced by tumor-stroma interaction in a subset of human breast cancers". Abstract:Background Communication between different cell types is a cardinal feature of multi-cellular organisms and perturbations ...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE7260: epithelial-mesenchymal interaction of the breast GSE7263: Effect of heterotypic interaction between breast cancer cell line MDA-MB231 and CCL-171 fibroblast Refer to individual Series
ORGANISM(S): Homo sapiens 
These 12 arrays are the basis for Figure 1 of the "An interferon-response induced by tumor-stroma interaction in a subset of human breast cancers" manuscript. Figure 1: Effect of heterotypic interaction between breast cancer cell line MDA-MB231 and CCL-171 fibroblast. Biologically indepen...
ORGANISM(S): Homo sapiens 
TGF-beta1 is the major cytokine driver of fibrotic scarring observed in diabetic nephropathy and other fibrosis-related diseases. RNA-sequencing offers the potential for more sensitive assessment of the TGF-M-CM-^_1-driven transcriptome. There were two treatment groups: vehicle, 48 hr TGFb1. Each tr...
ORGANISM(S): Homo sapiens 
Single-cell RNA-seq data for Trex1 WT and KO mice from the heart. Used for manuscript in submission at Science Advances.
ORGANISM(S): Mus musculus 
EWI-2 (IgSF8) plays a novel, bifunctional role in melanoma cells. EWI-2 inhibits migration, metastasis, EMT-like changes, and CD271-dependent invasion in multiple melanoma cell lines. On the other hand, EWI-2 supports melanoma cell proliferation, survival, and xenograft growth. Consistent with these...
ORGANISM(S): Homo sapiens 
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