Sort   by:  
 Page size 
TranscriptomicsSingle-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury
Heterogeneous pools of adult neural stem cells (NSCs) contribute to brain maintenance and regeneration after injury. The balance of NSC activation and quiescence, as well as the induction of lineage-specific transcription factors, may contribute to diversity of neuronal and glial fates. To identify ...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-67833 | biostudies-arrayexpress
TranscriptomicsSRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass
Increased expression of SIRT1 extends the lifespan of lower organisms and delays the onset of age-related diseases in mammals. Here, we show that SRT2104, a synthetic small molecule activator of SIRT1, extends both mean and maximal lifespan of mice fed a standard diet. This is accompanied by improve...
ORGANISM(S): Mus musculus 
2014-09-22 | E-GEOD-49000 | biostudies-arrayexpress
TranscriptomicsExpression data from mNSc after 48 hour of treatment with CD95L-T4
In neural stem cells, stimulation of the â??death receptorâ?? CD95 does not trigger apoptosis but resulted in increased stem cell survival and neuronal specification via activation of the Src /PI3K /AKT/mTOR signalling pathway. To further characterize CD95-dependent neural stem cell survival and dif...
ORGANISM(S): Mus musculus 
2010-03-09 | E-GEOD-15623 | biostudies-arrayexpress
UnknownInterferon regulates neural stem cell function at all ages by orchestrating mTOR and cell cycle
Not available
S-SCDT-10_15252-EMMM_202216434 | biostudies-other
Sort   by:  
 Page size